Evidence map›Paper›PMID 35637949›Full record

ArticleInternational journal of biological sciences2022

Neutrophil extracellular traps mediate m

Hao Zhang, Jinlong Liu, Yilu Zhou, Mengdi Qu, Yanghanzhao Wang, Kefang Guo, Ruling Shen, Zhirong Sun, Juan P Cata, Shuofei Yang and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 201 papers.

0numbers the graph read from it
0cells of the map it votes in
201citing papers in PubMed
25.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

201 citing papers in PubMed, 305 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Fecal microbiota transplantation alleviates sepsis-induced acute lung injury by improving mitochondrial function.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2026
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Macrophage Extracellular Traps in Immunity and Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  13. mRedox biology · 2026
    Review
  14. Article
  15. Alveolar macrophage-neutrophil crosstalk in acute lung injury: mechanisms, feedback loops, and therapeutic opportunities.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

141 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Hao ZhangDepartment of Anesthesiology, Zhongshan Hospital, Fudan University; Cancer Center, Zhongshan Hospital, Fudan University.
Jinlong LiuFudan Zhangjiang Institute, Shanghai 201203, China.
Yilu ZhouDepartment of Anesthesiology, Shanghai first Maternity and infant Hospital, Tongji University school of medicine, Shanghai, China.
Mengdi QuDepartment of Anesthesiology, Zhongshan Hospital, Fudan University; Cancer Center, Zhongshan Hospital, Fudan University.
Yanghanzhao WangDepartment of Anesthesiology, Zhongshan Hospital, Fudan University; Cancer Center, Zhongshan Hospital, Fudan University.
Kefang GuoDepartment of Anesthesiology, Zhongshan Hospital, Fudan University; Cancer Center, Zhongshan Hospital, Fudan University.
Ruling ShenShanghai Laboratory Animal Research Center, 201203, Shanghai, China.
Zhirong SunDepartment of Anesthesiology, Shanghai Cancer Center, Shanghai, China.
Juan P CataDepartment of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Centre, Houston, TX, United States.
Shuofei YangDepartment of Vascular Surgery, Renji Hospital,School of Medicine, Shanghai Jiaotong University, Shanghai, China.
Wankun ChenDepartment of Anesthesiology, Zhongshan Hospital, Fudan University; Cancer Center, Zhongshan Hospital, Fudan University.
Changhong MiaoDepartment of Anesthesiology, Zhongshan Hospital, Fudan University; Cancer Center, Zhongshan Hospital, Fudan University.
Fudan University · CNJinshan Hospital of Fudan University · CNThe University of Texas MD Anderson Cancer Center · USZhongshan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neutrophil extracellular traps (NETs) production is a major strategy employed by polymorphonuclear neutrophils (PMNs) to fight against microbes. NETs have been implicated in the pathogenesis of various lung injuries, although few studies have explored NETs in sepsis-associated acute lung injury (SI-ALI). Here, we demonstrate a major contribution of NETs to the pathology of sepsis-associated ALI by inducing ferroptosis of alveolar epithelial cells. Using both

Indexed as

Acute Lung InjuryExtracellular TrapsFerroptosisSepsisAlveolar Epithelial CellsAnimalsHumansMethyltransferasesMiceMethyltransferasesMETTL3 protein, humanferroptosisN6-MethylationNeutrophil extracellular trapssepsis-associated acute lung injury

Identifiers

PMID35637949
PMCPMC9134924
OpenAlexW4285159704

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.