ReviewJournal of ophthalmology2022
Corneal Endothelial Cell Loss in Glaucoma and Glaucoma Surgery and the Utility of Management with Descemet Membrane Endothelial Keratoplasty (DMEK).
Review in Journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 26 citations in OpenAlex.
- Comparative outcomes of DSAEK and DMEK in eyes with prior Ahmed glaucoma valve implantation.PloS one · 2026Article
- Current concepts and recent trends in endothelial keratoplasty.World journal of transplantation · 2025Review
- Incidence of Corneal Graft Failure with Glaucoma Drainage Device Placement in the Anterior Chamber Compared to the Ciliary Sulcus.Ophthalmology and therapy · 2025Article
- Randomized, Cross over, Multicenter, Single-Blind Study Comparing Citicoline 500 mg/Homotaurine 50 mg/Vitamin B3 54 mg/Pyrroloquinoline Quinone 5 mg (Neuprozin MitoJournal of clinical medicine · 2025Article
- Endothelial keratoplasty: indications and outcomes in a tertiary care center in Lebanon.BMC ophthalmology · 2025Article
- Research progress of corneal characteristics and changes in primary angle‑closure glaucoma (Review).Biomedical reports · 2025Review
- Article
- Glaucomatous retinal ganglion cells: death and protection.International journal of ophthalmology · 2025Review
- Bleb revision and transscleral cyclophotocoagulation for congenital glaucoma patient with Turner syndrome andInternational journal of ophthalmology · 2025Article
- Long-Term Surgical Outcome of Trabeculectomy with Mitomycin C: A Comparison Between Primary and Secondary Glaucoma in Thailand.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Corneal endothelial cell loss with different techniques of nucleus delivery in Manual Small Incision Cataract Surgery- Randomized Controlled Trial.Journal of cataract and refractive surgery · 2024Article
- Comparison of efficacy and safety between gonioscopy-assisted transluminal trabeculotomy and trabeculectomy for primary open-angle glaucoma treatment: a retrospective cohort study.BMC ophthalmology · 2024Article
- Integrated environmental and health economic assessments of novel xeno-keratografts addressing a growing public health crisis.Scientific reports · 2024Article
- A computational fluid dynamics investigation of endothelial cell damage from glaucoma drainage devices.Scientific reports · 2024Article
- Identification of hub genes for glaucoma: a study based on bioinformatics analysis and experimental verification.International journal of ophthalmology · 2023Article
- The Descemet Membrane Endothelial Keratoplasty (DMEK) "Wave Maneuver".Journal of clinical medicine · 2022Article
- Likelihood of Corneal Transplantation after Tube versus Trabeculectomy: An IRIS® Registry Study.Ophthalmology. GlaucomaArticle
- Glaucoma surgery success and corneal graft survival in patients with prior corneal transplantation: A retrospective cohort study.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological SocietyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The corneal endothelium has a crucial role in maintaining a clear and healthy cornea. Corneal endothelial cell loss occurs naturally with age; however, a diagnosis of glaucoma and surgical intervention for glaucoma can exacerbate a decline in cell number and impairment in morphology. In glaucoma, the mechanisms for this are not well understood and this accelerated cell loss can result in corneal decompensation. Given the high prevalence of glaucoma worldwide, this review aims to explore the abnormalities observed in the corneal endothelium in differing glaucoma phenotypes and glaucoma therapies (medical or surgical including with new generation microinvasive glaucoma surgeries). Descemet membrane endothelial keratoplasty (DMEK) is increasingly being used to manage corneal endothelial failure for glaucoma patients and we aim to review the recent literature evaluating the use of this technique in this clinical scenario.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.