Evidence map›Paper›PMID 35637624›Full record

Trial reportJournal of psychopharmacology (Oxford, England)2022

Effects of cannabidiol on simulated driving and cognitive performance: A dose-ranging randomised controlled trial.

Danielle McCartney, Anastasia S Suraev, Peter T Doohan, Christopher Irwin, Richard C Kevin, Ronald R Grunstein, Camilla M Hoyos, Iain S McGregor

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of psychopharmacology (Oxford, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Does acute cannabidiol (CBD) use impair performance? A meta-analysis and comparison with placebo and delta-9-tetrahydrocannabinol (THC).Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Pooled it
  2. The "Next Day" Effects of Cannabis Use: A Systematic Review.Cannabis and cannabinoid research · 2023
    Pooled it
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  7. Detection of ΔDrug testing and analysis · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Danielle McCartneyLambert Initiative for Cannabinoid Therapeutics, The University of Sydney, Sydney, NSW, Australia.ORCID 0000-0002-7783-5220
Anastasia S SuraevLambert Initiative for Cannabinoid Therapeutics, The University of Sydney, Sydney, NSW, Australia.
Peter T DoohanLambert Initiative for Cannabinoid Therapeutics, The University of Sydney, Sydney, NSW, Australia.
Christopher IrwinSchool of Health Sciences and Social Work, Griffith University, Gold Coast, QLD, Australia.
Richard C KevinLambert Initiative for Cannabinoid Therapeutics, The University of Sydney, Sydney, NSW, Australia.
Ronald R GrunsteinCentre for Sleep and Chronobiology, Woolcock Institute of Medical Research, Sydney, NSW, Australia.
Camilla M HoyosBrain and Mind Centre, The University of Sydney, Sydney, NSW, Australia.
Iain S McGregorLambert Initiative for Cannabinoid Therapeutics, The University of Sydney, Sydney, NSW, Australia.
The University of Sydney · AUGriffith University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCannabidiol (CBD), a major cannabinoid of

aimWe investigated the effects of CBD on driving performance.

methodsHealthy adults (

resultsNon-inferiority was established during the standard component of Drive 1 and CF component of Drive 2 on all CBD treatments and during the standard component of Drive 2 on the 15 and 1500 mg treatments (95% CIs < 0.5). The remaining comparisons to placebo were inconclusive (the 95% CIs included 0 and 0.50). No dose of CBD impaired cognition or induced feelings of intoxication (

conclusionAcute, oral CBD treatment does not appear to induce feelings of intoxication and is unlikely to impair cognitive function or driving performance (Registration: ACTRN12619001552178).

Indexed as

CannabidiolCannabisAdultBlood Alcohol ContentCognitionCross-Over StudiesDouble-Blind MethodDronabinolHumansBlood Alcohol ContentCannabidiolDronabinolCannabidiolcognitiondriving simulationmedicinal cannabispsychomotor

Identifiers

PMID35637624
PMCPMC9716488
OpenAlexW4281803605

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.