Evidence map›Paper›PMID 35637622›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2022

Design, synthesis, molecular modeling and biological evaluation of novel Benzoxazole-Benzamide conjugates

Ibrahim H Eissa, Radwan El-Haggar, Mohammed A Dahab, Marwa F Ahmed, Hazem A Mahdy, Reem I Alsantali, Alaa Elwan, Nicolas Masurier, Samar S Fatahala

Open access · goldAbstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. NovelJournal of enzyme inhibition and medicinal chemistry · 2023
    Article
  7. Article
  8. Design, synthesis,RSC advances · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Ibrahim H EissaPharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.ORCID 0000-0002-6955-2263
Radwan El-HaggarPharmaceutical Chemistry Department, Faculty of Pharmacy, Helwan University, Cairo, Egypt.
Mohammed A DahabPharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
Marwa F AhmedPharmaceutical Chemistry Department, Faculty of Pharmacy, Helwan University, Cairo, Egypt.
Hazem A MahdyPharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.ORCID 0000-0002-6620-241X
Reem I AlsantaliDepartment of Pharmaceutical Chemistry, College of Pharmacy, Taif University, Taif, Saudi Arabia.
Alaa ElwanPharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
Nicolas MasurierInstitut des Biomolécules Max Mousseron (IBMM), UMR 5247, CNRS, Université de Montpellier, ENSCM, Montpellier, France.ORCID 0000-0001-9169-8149
Samar S FatahalaPharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Helwan University, Cairo, Egypt.
Al-Azhar University · EGÉcole Nationale Supérieure de Chimie de Montpellier · FRTaif University · SAHelwan University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel series of 2-thioacetamide linked benzoxazole-benzamide conjugates

Indexed as

BenzoxazolesVascular Endothelial Growth Factor Receptor-2ApoptosisBenzamidesDrug DesignFibroblastsHCT116 CellsHumansMCF-7 CellsMolecular Docking SimulationMolecular StructureStructure-Activity RelationshipBenzamidesBenzoxazolesVascular Endothelial Growth Factor Receptor-2anti-cancerapoptosisBcl-2Benzoxazole-benzamideVEGFR-2 inhibitors

Identifiers

PMID35637622
PMCPMC9176662
OpenAlexW4281765747

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.