ArticleJournal of the American Geriatrics Society2022
Patients living with dementia have worse outcomes when undergoing high-risk procedures.
Article in Journal of the American Geriatrics Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 26 citations in OpenAlex.
- Clinician Considerations Regarding Surgical Decision-Making in the Context of Dementia.JAMA surgery · 2026Article
- Long-Term Cognitive and Functional Outcomes of Anesthesia and Surgery in Patients with Dementia.Healthcare (Basel, Switzerland) · 2026Review
- Incidence and Outcomes of Unplanned Intensive Interventions After Common Inpatient Surgeries: A Population-Based Cohort Study.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2026Article
- Dementia Is Associated With Adverse Outcomes After Nonruptured Abdominal Aortic Aneurysm Repair.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2026Article
- Racial and Sex Differences in Postoperative Mortality Between Patients With Versus Without Dementia.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2026Article
- Outcomes Among Patients With End-stage Kidney Disease and Chronic Limb-threatening Ischemia: A Population-based Cohort Study.Annals of surgery · 2026Article
- Dementia Is Associated With Higher One-Year Mortality and Worse Patient-Centered Outcomes in Patients Undergoing Percutaneous Coronary Intervention for Acute Myocardial Infarction and Cardiogenic Shock.Cardiology research · 2026Article
- Practice, Policy, and Research Recommendations to Improve Decision-Making about Surgery for People Living with Dementia: A Delphi Panel Consensus.Annals of surgery · 2026Article
- Dementia is associated with higher mortality and worse patient-centered outcomes after complex and high-risk coronary artery stenting.American heart journal plus : cardiology research and practice · 2026Article
- Patients With Dementia Undergoing High-Risk Inpatient Surgery Have Poor Outcomes.Journal of the American Geriatrics Society · 2025Article
- Complications of gastrostomy tube placement in patients with dementia: a national inpatient analysis.Surgical endoscopy · 2025Article
- Preoperative dementia in patients undergoing coronary artery bypass grafting: A propensity-matched analysis.Surgery · 2025Article
- Medical decision-making experiences of persons with dementia and their carepartners: a qualitative study.BMC palliative care · 2025Article
- Cognitive Impairment is Common and Unrecognized in Vascular Surgery Patients.Annals of vascular surgery · 2025Observational
- Colorectal Surgery Outcomes and Healthcare Burden for Medicare Beneficiaries With Dementia.The Journal of surgical research · 2025Article
- Patients with dementia or frailty undergoing major limb amputation have poor outcomes.Journal of vascular surgery · 2025Article
- The Impact of Comorbid Dementia and Diabetes Mellitus on Hospital Patients' Outcomes: A Systematic Review and Meta-analysis.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025Article
- Estimating the burden of dementia and parkinsonism through a novel identification algorithm based on healthcare administrative data.Frontiers in public health · 2025Article
- Factors associated with care partner identification and education among hospitalized persons living with dementia.PEC innovation · 2024Article
- Receipt of Home Health and 30-day Outcomes Among Veterans With Dementia Following Inpatient Surgery.Journal of the American Medical Directors Association · 2024Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundPatients with Alzheimer's Disease and Related Dementias (ADRD) undergoing inpatient procedures represent a population at elevated risk for adverse outcomes including postoperative complications, mortality, and discharge to a higher level of care. Outcomes may be particularly poor in patients with ADRD undergoing high-risk procedures. We sought to determine traditional (e.g., 30-day mortality) and patient-centered (e.g., discharge disposition) outcomes in patients with ADRD undergoing high-risk inpatient procedures.
methodsThis retrospective cohort study analyzed electronic health records linked to fee-for-service Medicare claims data at a tertiary care academic health system. All patients from a large multi-hospital health system undergoing high-risk inpatient procedures from October 1, 2015 to September 30, 2017 with continuous Medicare Parts A and B enrollment in the 12 months prior to and 90 days following the procedure were included.
resultsThis study included 6779 patients. 536 (7.9%) had ADRD. A multivariable analysis of outcomes demonstrated higher risks for postoperative complications (OR 1.49, 95% CI 1.23-1.81) and 90-day mortality (OR 1.44 [95% CI 1.09-1.91]) in patients with ADRD compared to those without. Patients with ADRD were more likely to be discharged to a higher level of care (OR 1.70, 95% CI 1.32-2.18) and only 37.3% of patients admitted from home were discharged to home.
conclusionsCompared to those without ADRD, patients living with ADRD undergoing high-risk procedures have poor traditional and patient-centered outcomes including increased risks for 90-day mortality, postoperative complications, longer hospital lengths of stay, and discharge to a higher level of care. These data may be used by patients, their surrogates, and their physicians to help align surgical decision-making with health care goals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.