Evidence map›Paper›PMID 35637220›Full record

ArticleNPJ primary care respiratory medicine2022

Medication availability and economic barriers to adherence in asthma and COPD patients in low-resource settings.

Aizhamal Tabyshova, Talant Sooronbaev, Azamat Akylbekov, Maamed Mademilov, Aida Isakova, Aidai Erkinbaeva, Kamila Magdieva, Niels H Chavannes, Maarten J Postma, Job F M van Boven

Open access · goldAbstract read
In one paragraph

Article in NPJ primary care respiratory medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 36 citations in OpenAlex.

  1. Consistent adherence to biologic therapies is critical for improving outcomes in asthma.The journal of allergy and clinical immunology. Global · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Aizhamal TabyshovaUniversity Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, Groningen, The Netherlands. aljimon@mail.ru.ORCID 0000-0002-4850-7746
Talant SooronbaevPulmonology Department, National Center of Cardiology and Internal Medicine named after M.M. Mirrakhimov, Bishkek, Kyrgyzstan.
Azamat AkylbekovPulmonology Department, National Center of Cardiology and Internal Medicine named after M.M. Mirrakhimov, Bishkek, Kyrgyzstan.
Maamed MademilovPulmonology Department, National Center of Cardiology and Internal Medicine named after M.M. Mirrakhimov, Bishkek, Kyrgyzstan.ORCID 0000-0001-8528-3115
Aida IsakovaPulmonology Department, Jalal-Abad Regional Hospital, Jalal-Abad, Kyrgyzstan.
Aidai ErkinbaevaKyrgyz State Medical Institute of Post-Graduating Training and Continuous Education, Bishkek, Kyrgyzstan.
Kamila MagdievaKyrgyz State Medical Institute of Post-Graduating Training and Continuous Education, Bishkek, Kyrgyzstan.
Niels H ChavannesDepartment of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-8607-9199
Maarten J PostmaDepartment of Health Sciences, Unit of Global Health, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Job F M van BovenUniversity Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, Groningen, The Netherlands.
National Center of Cardiology and Internal Medicine · KGUniversity Medical Center Groningen · NLKyrgyz State Medical Academy · KGJalalabad State University · KGLeiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inhaled medication is essential to control asthma and COPD, but availability and proper adherence are challenges in low-middle income countries (LMIC). Data on medication availability and adherence in Central Asia are lacking. We aimed to investigate the availability of respiratory medication and the extent of financially driven non-adherence in patients with COPD and asthma in Kyrgyzstan. A cross-sectional study was conducted in two regions of Kyrgyzstan. Patients with a physician- and spirometry confirmed diagnosis of asthma and/or COPD were included. The main outcomes were (1) availability of respiratory medication in hospitals and pharmacies, assessed by a survey, and (2) medication adherence, assessed by the Test of Adherence to Inhalers (TAI). Logistic regression analyses were used to identify predictors for adherence. Of the 300 participants (COPD: 264; asthma: 36), 68.9% were buying respiratory medication out-of-pocket. Of all patients visiting the hospital, almost half reported medication not being available. In pharmacies, this was 8%. Poor adherence prevailed over intermediate and good adherence (80.7% vs. 12.0% and 7.3%, respectively). Deliberate and erratic non-adherence behavior patterns were the most frequent (89.7% and 88.0%), followed by an unconscious non-adherent behavioral pattern (31.3%). In total, 68.3% reported a financial reason as a barrier to proper adherence. Low BMI was the only factor significantly associated with good adherence. In this LMIC population, poor medication availability was common and 80% were poorly adherent. Erratic and deliberate non-adherent behaviors were the most common pattern and financial barriers play a role in over two-thirds of the population.

Indexed as

AsthmaPulmonary Disease, Chronic ObstructiveCross-Sectional StudiesHumansMedication AdherenceNebulizers and Vaporizers

Identifiers

PMID35637220
PMCPMC9151780
OpenAlexW4281661460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.