Evidence map›Paper›PMID 35636949›Full record

ReviewJournal of neurointerventional surgery2023

Bioresorbable flow diverters for the treatment of intracranial aneurysms: review of current literature and future directions.

Alexander A Oliver, Kent D Carlson, Cem Bilgin, Jorge L Arturo Larco, Ramanathan Kadirvel, Roger J Guillory, Dan Dragomir Daescu, David F Kallmes

Open access · greenAbstract readReview
In one paragraph

Review in Journal of neurointerventional surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Thrombogenicity of biodegradable metals.Bioactive materials · 2024
    Article
  9. Review
  10. Intraluminal Flow Diverter Design Primer for Neurointerventionalists.AJNR. American journal of neuroradiology · 2024
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Alexander A OliverBiomedical Engineering and Physiology, Mayo Clinic Graduate School of Biomedical Sciences, Rochester, Minnesota, USA Oliver.Alexander@mayo.edu aaoliver@mtu.edu.ORCID http://orcid.org/0000-0002-7283-2063
Kent D CarlsonPhysiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.
Cem BilginRadiology, Mayo Clinic, Rochester, Minnesota, USA.
Jorge L Arturo LarcoNeurosurgery, Mayo Clinic, Rochester, Minnesota, USA.ORCID http://orcid.org/0000-0002-8259-2681
Ramanathan KadirvelRadiology, Mayo Clinic, Rochester, Minnesota, USA.ORCID http://orcid.org/0000-0002-6786-9953
Roger J GuilloryBiomedical Engineering, Michigan Technological University, Houghton, Michigan, USA.
Dan Dragomir DaescuBiomedical Engineering and Physiology, Mayo Clinic Graduate School of Biomedical Sciences, Rochester, Minnesota, USA.
David F KallmesBiomedical Engineering and Physiology, Mayo Clinic Graduate School of Biomedical Sciences, Rochester, Minnesota, USA.
Mayo Clinic · USMichigan Technological University · US

Funding

Computational and Biological Approach to Flow DiversionR01NS076491 · NINDS · MAYO CLINIC ROCHESTER · PI Juan R Cebral, DAVID F KALLMES · 2011 to 2026
$7.4M
NINDS NIH HHS R01 NS076491
6 · The paper itself

Abstract

The use of flow diverters is a rapidly growing endovascular approach for the treatment of intracranial aneurysms. All FDA-approved flow diverters are composed of nitinol or cobalt-chromium, which will remain in the patient for the duration of their life. Bioresorbable flow diverters have been proposed by several independent investigators as the next generation of flow diverting devices. These devices aim to serve their transient function of occluding and healing the aneurysm prior to being safely resorbed by the body, eliminating complications associated with the permanent presence of conventional flow diverters. Theoretical advantages of bioresorbable flow diverters include (1) reduction in device-induced thrombosis; (2) reduction in chronic inflammation and device-induced stenosis; (3) reduction in side branch occlusion; (4) restoration of physiological vasomotor function; (5) reduction in imaging artifacts; and (6) use in pediatric applications. Advances made in the similar bioresorbable coronary stenting field highlight some of these advantages and demonstrate the feasibility and safety of bioresorbable endovascular devices in the clinic. The current work aims to review the progress of bioresorbable flow diverters, identify opportunities for further investigation, and ultimately stimulate the advancement of this technology.

Indexed as

Embolization, TherapeuticEndovascular ProceduresIntracranial AneurysmAbsorbable ImplantsChildHumansStentsTreatment OutcomeAneurysmFlow DiverterMaterialStent

Identifiers

PMID35636949
PMCPMC9708930
OpenAlexW4282048613

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.