ArticleNeuroImage2022
Eyes-closed versus eyes-open differences in spontaneous neural dynamics during development.
Article in NeuroImage, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 39 citations in OpenAlex.
- Prefrontal hemodynamic alterations during resting state and stroop interference in cognitively healthy older adults with high plasma pTau-217 levels.Neuroimage. Reports · 2026Article
- Age-dependent modulations of hemispheric small-world networks in different eye states: resting-state electroencephalogram research.GeroScience · 2026Article
- Alpha Reactivity Dynamics Reveal Multi-System Variability Without Global Alpha Slowing in Fragile X Syndrome.Research square · 2026Article
- Atypical Resting-State EEG Graph Metrics of Network Efficiency Across Development in Autism and Their Association with Social Cognition: Results from the LEAP Study.Journal of autism and developmental disorders · 2026Article
- Microsphere-Templated Conductive Syntactic Foams for Recyclable and Additively Manufactured Soft Electronics.Advanced healthcare materials · 2026Article
- Normative modeling of MEG brain oscillations across the human lifespan.Communications biology · 2026Article
- Frequency-specific resting-state EEG modulation during eyes-closed and eyes-open transitions in female soccer players.Frontiers in psychology · 2026Article
- Electroencephalogram Gamma Band Power Correlates with Anhedonia in a Community Sample.Journal of personalized medicine · 2025Article
- Stimulus-Evoked Brain Signals for Parkinson's Detection: A Comprehensive Benchmark Performance Analysis on Cross-Stimulation and Channel-Wise Experiments.Bioengineering (Basel, Switzerland) · 2025Article
- Spatiotemporal dynamics of multispectral oscillatory activity underlying the processing of negative and positive emotional images.NeuroImage · 2025Article
- Resting State Electroencephalography (EEG) Reveals Atypical Oscillatory Power in Children With Development Coordination Disorder (DCD).Psychophysiology · 2025Article
- Oscillatory brain dynamics underlying affective face processing.Social cognitive and affective neuroscience · 2025Article
- Enhanced classification of tinnitus patients using EEG microstates and deep learning techniques.Scientific reports · 2025Article
- ESENA: A Novel Spatiotemporal Event Network Information Approach for Mining Scalp EEG Data.Brain and behavior · 2025Article
- Interactive effects of social media use and puberty on resting-state cortical activity and mental health symptoms.Developmental cognitive neuroscience · 2025Article
- EEG differences in competitive female gymnastics, soccer, and esports athletes between resting states with eyes closed and open.Scientific reports · 2024Article
- A Novel Time-Frequency Parameterization Method for Oscillations in Specific Frequency Bands and Its Application on OPM-MEG.Bioengineering (Basel, Switzerland) · 2024Article
- Sexual dimorphism in cortical theta rhythms relates to elevated internalizing symptoms during adolescence.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Spontaneous cortical activity is altered in persons with HIV and related to domain-specific cognitive function.Brain communications · 2024Article
- Developmental changes in endogenous testosterone have sexually-dimorphic effects on spontaneous cortical dynamics.Human brain mapping · 2023Article
Corrections and comments
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Authors and funding
10 authors at 7 institutions in 1 country.
Funding
Abstract
backgroundAssessing brain activity during rest has become a widely used approach in developmental neuroscience. Extant literature has measured resting brain activity both during eyes-open and eyes-closed conditions, but the difference between these conditions has not yet been well characterized. Studies, limited to fMRI and EEG, have suggested that eyes-open versus -closed conditions may differentially impact neural activity, especially in visual cortices.
methodsSpontaneous cortical activity was recorded using MEG from 108 typically developing youth (9-15 years-old; 55 female) during separate sessions of eyes-open and eyes-closed rest. MEG source images were computed, and the strength of spontaneous neural activity was estimated in the canonical delta, theta, alpha, beta, and gamma bands, respectively. Power spectral density maps for eyes-open were subtracted from eyes-closed rest, and then submitted to vertex-wise regression models to identify spatially specific differences between conditions and as a function of age and sex.
resultsRelative alpha power was weaker in the eyes-open compared to -closed condition, but otherwise eyes-open was stronger in all frequency bands, with differences concentrated in the occipital cortex. Relative theta power became stronger in the eyes-open compared to the eyes-closed condition with increasing age in frontal cortex. No differences were observed between males and females.
conclusionsThe differences in relative power from eyes-closed to -open conditions are consistent with changes observed in task-based visual sensory responses. Age differences occurred in relatively late developing frontal regions, consistent with canonical attention regions, suggesting that these differences could be reflective of developmental changes in attention processes during puberty. Taken together, resting-state paradigms using eyes-open versus -closed produce distinct results and, in fact, can help pinpoint sensory related brain activity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.