Evidence map›Paper›PMID 35636454›Full record

SynthesisZeitschrift fur Gastroenterologie2022

Efficacy of aerobic and resistance exercises in improving visceral adipose in patients with non-alcoholic fatty liver: a meta-analysis of randomized controlled trials.

Lixiang Fu, Wenyue Zhang, Yupei Ao, Zhongling Zheng, Huaidong Hu

Open access · hybridAbstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Zeitschrift fur Gastroenterologie, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lixiang FuThe Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Wenyue ZhangThe Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yupei AoThe Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Zhongling ZhengThe Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Huaidong HuThe Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID 0000-0003-2332-2304
Dalian Medical University · CN

Funding

2017ZX10202203-007;2017ZX10202203-008 The National Science and Technology Major Project of China
6 · The paper itself

Abstract

backgroundNon-alcoholic fatty liver disease (NAFLD) is a common chronic disease that can cause liver deterioration if insufficiently diagnosed and untreated. The verification of whether exercise interventions improve liver enzymes and lipid and glucose parameters is scant.

aimWe conducted this systematic review and meta-analysis to examine the efficacy of aerobic and resistance exercise interventions in patients with NAFLD.

methodsWe searched the related studies in the PubMed, Embase, Cochrane Library, and Web of Science databases. We screened 1129 articles published before September 1, 2021, based on the inclusion and exclusion standards, after which 17 articles with a total of 1168 participants were finally included. The indices of liver enzymes and lipid and glucose metabolism were gathered and examined by Stata SE.

resultsThe outcomes suggested that aerobic and resistance exercise can markedly improve the parameters of liver enzymes, blood lipids, and glucose, and especially visceral adipose tissue (weighted mean different [WMD] = -8.3 at 95% CI [-11.59 to -5.00], p < 0.0001), in patients with NAFLD.

conclusionThis study demonstrated that aerobic and resistance exercises positively affect NAFLD treatment. To further quantify the effects on patients with NAFLD, a more specific and uniform exercise program should be proposed.

Indexed as

Non-alcoholic Fatty Liver DiseaseResistance TrainingExercise TherapyGlucoseHumansLipidsRandomized Controlled Trials as TopicGlucoseLipids

Identifiers

PMID35636454
PMCPMC9661875
OpenAlexW4281749694

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.