Evidence map›Paper›PMID 35636428›Full record

ArticleVeterinary medicine and science2022

Phylogenetic analysis of porcine circovirus 3 circulating in Canadian pigs.

Maodong Zhang, Chao Chun Liu, Yanyun Huang, Janet E Hill, Maria Bravo Araya, Davor Ojkic, Carl A Gagnon

Open access · goldAbstract read
In one paragraph

Article in Veterinary medicine and science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Maodong ZhangPrairie Diagnostic Services Inc., Saskatoon, Saskatchewan, Canada.ORCID 0000-0002-9565-3017
Chao Chun LiuDepartment of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada.
Yanyun HuangPrairie Diagnostic Services Inc., Saskatoon, Saskatchewan, Canada.
Janet E HillDepartment of Veterinary Microbiology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID 0000-0002-2187-6277
Maria Bravo ArayaPrairie Diagnostic Services Inc., Saskatoon, Saskatchewan, Canada.
Davor OjkicAnimal Health Laboratory, University of Guelph, Guelph, Ontario, Canada.
Carl A GagnonMolecular Diagnostic Laboratory of Centre de Diagnostic Vétérinaire de universitas de Montréal (CDVUM) and Swine and Poultry Infectious Diseases Research Center (CRIPA-FRQNT), Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, Quebec, Canada.
University of Saskatchewan · CAShared Health · CASimon Fraser University · CAUniversité de Montréal · CAUniversity of Guelph · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPorcine circovirus 3 (PCV3) has been detected in pigs worldwide and associated with several clinical signs.

methodsTo investigate the genetic diversity of PCV3 strains circulating in Canada, 44 PCV3 positive samples from Saskatchewan (2/44), Manitoba (2/44), Quebec (4/44), Alberta (11/44) and Ontario (25/44) submitted to diagnostic laboratories in Canada between 2019 and 2021 were sequenced and analyzed.

resultsPhylogenetic analysis of capsid genes showed that all of the 44 Canadian strains classified into PCV3a and segregated into seven lineages with common amino acid changes observed at A24V, R27K, N56D, T77S, Q98R, L150I (F) and R168K positions.

conclusionFuture studies are required to determine whether the polymorphisms in capsid proteins, as revealed in this study, could be associated with differences in the pathogenicity or antigenicity of PCV3 strains. This is the first phylogenetic analysis of PCV3 strains among different provinces in Canada.

Indexed as

Circoviridae InfectionsCircovirusSwine DiseasesAmino AcidsAnimalsCanadaCapsid ProteinsPhylogenySwineAmino AcidsCapsid ProteinsCanadian pigsphylogenetic analysisporcine circovirus 3

Identifiers

PMID35636428
PMCPMC9514502
OpenAlexW4281723872

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.