Evidence map›Paper›PMID 35636344›Full record

ArticleDevelopmental cognitive neuroscience2022

Real-time motion monitoring improves functional MRI data quality in infants.

Carolina Badke D'Andrea, Jeanette K Kenley, David F Montez, Amy E Mirro, Ryland L Miller, Eric A Earl, Jonathan M Koller, Sooyeon Sung, Essa Yacoub, Jed T Elison and 5 more

Abstract read
In one paragraph

Article in Developmental cognitive neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Considerations for conducting developmental neuroimaging research on mental health topics.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  5. Structure-function coupling in the first month of life: Associations with age and attention.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Functional parcellation of the neonatal cortical surface.Cerebral cortex (New York, N.Y. : 1991) · 2024
    Article
  10. Functional parcellation of the neonatal brain.bioRxiv : the preprint server for biology · 2023
    Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Carolina Badke D'AndreaDepartment of Cognitive Science, University of California San Diego, La Jolla, CA 92093, USA; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address: carolinabdandrea@email.wustl.edu.
Jeanette K KenleyDepartment of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
David F MontezDepartment of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Amy E MirroDepartment of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA.
Ryland L MillerDepartment of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Eric A EarlData Science and Sharing Team, National Institute of Mental Health, NIH, DHHS, Bethesda, MD 20899, USA.
Jonathan M KollerDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, USA.
Sooyeon SungInstitute of Child Development, College of Education and Human Development, University of Minnesota, Minneapolis, MN 55455, USA; Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Essa YacoubCenter for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, MN 55455, USA.
Jed T ElisonInstitute of Child Development, College of Education and Human Development, University of Minnesota, Minneapolis, MN 55455, USA; Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Damien A FairInstitute of Child Development, College of Education and Human Development, University of Minnesota, Minneapolis, MN 55455, USA; Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN 55455, USA; Masonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN 55455, USA.
Nico U F DosenbachDepartment of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA; Program in Occupational Therapy, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA.
Cynthia E RogersDepartment of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Christopher D SmyserDepartment of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA.
Deanna J GreeneDepartment of Cognitive Science, University of California San Diego, La Jolla, CA 92093, USA.

Funding

Early Life Adversity, Biological Embedding, and Risk for Developmental Precursors of Mental DisordersR01MH113883 · NIMH · WASHINGTON UNIVERSITY · PI JOAN L. LUBY, Christopher Daniel Smyser · 2018 to 2026
$20.6M
WUIDDRC Supplement-Supporting the health and well-being of children with intellectual and developmental disability during COVID-19 pandemicP50HD103525 · NICHD · WASHINGTON UNIVERSITY · PI JEFFREY D MILBRANDT · 2020 to 2026
$15.5M
Motion-robust brain MRI for infantsR44MH124567 · NIMH · TURING MEDICAL TECHNOLOGIES INC · PI BERTOLERO, MAXWELL, FAIR, DAMIEN A · 2020 to 2023
$7.3M
Visual biofeedback to reduce head motion during MRI scansR44MH122066 · NIMH · TURING MEDICAL TECHNOLOGIES INC · PI BRUENER, KEN, FAIR, DAMIEN A · 2019 to 2022
$6.2M
Solving the MRI motion problem with Framewise Integrated Real-Time MRI Monitoring (FIRMM) softwareR44MH121276 · NIMH · TURING MEDICAL TECHNOLOGIES INC · PI FAIR, DAMIEN A, ROTHNEY, MEGAN PEARL · 2020 to 2023
$5.4M
THE PRETERM BEHAVIORAL PHENOTYPE: TRAJECTORIES OF PSYCHOPATHOLOGY & CHANGES IN CEREBRAL CONNECTIVITYR01MH113570 · NIMH · WASHINGTON UNIVERSITY · PI ROGERS, CYNTHIA ELISE, SMYSER, CHRISTOPHER DANIEL · 2017 to 2021
$3.1M
UNDERSTANDING NEUROBEHAVIORAL DEFICITS IN PRETERM INFANTS THROUGH IMAGINGR01HD057098 · NICHD · WASHINGTON UNIVERSITY · PI INDER, TERRIE E, NEIL, JEFFREY J. · 2008 to 2012
$2.9M
PREDICTING FETAL ACIDEMIA WITH INTRAPARTUM ELECTRONIC FETAL HEART RATE MONITORINGR01HD061619 · NICHD · WASHINGTON UNIVERSITY · PI CAHILL, ALISON G, MACONES, GEORGE A · 2010 to 2014
$2.9M
Comprehensive Human Expressed Sequences in Brain (CHESS-BRAIN) and their roles in neuropsychiatric illnessR01MH123567 · NIMH · JOHNS HOPKINS UNIVERSITY · PI SALZBERG, STEVEN L. · 2021 to 2025
$2.8M
PREDICTING CHILDHOOD OUTCOMES IN PRETERM INFANTS USING CEREBRAL CONNECTIVITYK02NS089852 · NINDS · WASHINGTON UNIVERSITY · PI SMYSER, CHRISTOPHER DANIEL · 2014 to 2018
$848k
NICHD NIH HHS P50 HD103525NICHD NIH HHS R01 HD057098NICHD NIH HHS R01 HD061619NIMH NIH HHS R01 MH113570NIMH NIH HHS R01 MH113883NIMH NIH HHS R01 MH123567NIMH NIH HHS R44 MH121276NIMH NIH HHS R44 MH122066NIMH NIH HHS R44 MH124567NINDS NIH HHS K02 NS089852
6 · The paper itself

Abstract

Imaging the infant brain with MRI has improved our understanding of early neurodevelopment. However, head motion during MRI acquisition is detrimental to both functional and structural MRI scan quality. Though infants are typically scanned while asleep, they commonly exhibit motion during scanning causing data loss. Our group has shown that providing MRI technicians with real-time motion estimates via Framewise Integrated Real-Time MRI Monitoring (FIRMM) software helps obtain high-quality, low motion fMRI data. By estimating head motion in real time and displaying motion metrics to the MR technician during an fMRI scan, FIRMM can improve scanning efficiency. Here, we compared average framewise displacement (FD), a proxy for head motion, and the amount of usable fMRI data (FD ≤ 0.2 mm) in infants scanned with (n = 407) and without FIRMM (n = 295). Using a mixed-effects model, we found that the addition of FIRMM to current state-of-the-art infant scanning protocols significantly increased the amount of usable fMRI data acquired per infant, demonstrating its value for research and clinical infant neuroimaging.

Indexed as

ArtifactsHead MovementsBrainData AccuracyHumansMagnetic Resonance ImagingMotionFunctional MRIHead motionInfant brainNeurodevelopmentNeuroimaging

Identifiers

PMID35636344
PMCPMC9157440

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.