GuidelineAnaesthesia, critical care & pain medicine2022
Guidelines for the management of patients with severe acute pancreatitis, 2021.
Guideline in Anaesthesia, critical care & pain medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07714850 (Early Upper Gastrointestinal Endoscopic Findings as Predictors of Disease Course and Severity in Acute Pancreatitis), which is not on this map. Cited by 58 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Early Upper Gastrointestinal Endoscopic Findings as Predictors of Disease Course and Severity in Acute Pancreatitis: A Prospective Observational Cohort Study
Who cites it
58 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Comparison of clinical outcomes between aggressive and non-aggressive intravenous hydration for acute pancreatitis: a systematic review and meta-analysis.Critical care (London, England) · 2023Pooled it
- Prognostic value of C-reactive protein-to-albumin ratio in acute pancreatitis: a systematic review and meta-analysis.F1000Research · 2023Pooled it
- Thoracic epidural analgesia in intensive care unit patients with acute pancreatitis: the EPIPAN multicenter randomized controlled trial.Critical care (London, England) · 2023Trial
- Critical Care Management of Severe Acute Pancreatitis: Current Concepts, Clinical Challenges, and Future Perspectives.Life (Basel, Switzerland) · 2026Review
- Efficacy and safety of pharmacological and procedural interventions in the management of hypertriglyceridemia-induced acute pancreatitis: a systematic review.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2026Review
- Chitooligosaccharides Improves Severe Acute Pancreatitis by Reducing Intestinal Mucosal Injury and Regulating Intestinal Microbiota.Probiotics and antimicrobial proteins · 2026Article
- Article
- Insulin is central, plasmapheresis is salvage: clinical spectrum and management of severe hypertriglyceridemia in 21 children with diabetic ketoacidosis.Frontiers in endocrinology · 2026Article
- Clinical utility of the lactate-to-albumin ratio for predicting mortality in elderly severe acute pancreatitis.Frontiers in medicine · 2026Article
- Early prognostic value of the lactate-to-albumin ratio in severe acute pancreatitis with acute respiratory distress syndrome.Frontiers in medicine · 2026Article
- Effect of early prophylactic heparin use on prognosis in critically ill patients with acute pancreatitis: a retrospective cohort study.Scientific reports · 2025Article
- Acute Pancreatitis Management and Scoring in the Department of General Surgery, Northwick Park Hospital, 2022-2024.Cureus · 2025Article
- Anticoagulation therapy for intra-abdominal hypertension in patients with acute pancreatitis.BMC gastroenterology · 2025Article
- Annexin A1 mRNA-loaded liposomes alleviate acute pancreatitis by suppressing STING pathway and promoting efferocytosis in macrophages.Nature nanotechnology · 2025Article
- Computed tomography features of recurrent acute pancreatitis based on different etiologies.Quantitative imaging in medicine and surgery · 2025Article
- Application of continuous renal replacement therapy (CRRT) in patients with severe acute pancreatitis: an analytical study.BMC gastroenterology · 2025Article
- Current Progress in the CT- and MRI-Based Detection and Evaluation of Acute Pancreatitis Complications.Medical science monitor : international medical journal of experimental and clinical research · 2025Review
- Diagnostic and therapeutic management of severe acute pancreatitis. Evidence based medicine (EBM) clinical practice guidelines.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2025Article
- Maternal and fetal death associated with acute pancreatitis during pregnancy: A case report.World journal of clinical cases · 2025Article
- Adjuvant non-opioid analgesics decrease in-hospital mortality in targeted patients with acute pancreatitis receiving opioids.European journal of gastroenterology & hepatology · 2025Article
Corrections and comments
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Authors and funding
24 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo provide guidelines for the management of the intensive care patient with severe acute pancreatitis.
designA consensus committee of 22 experts was convened. A formal conflict-of-interest (COI) policy was developed at the beginning of the process and enforced throughout. The entire guideline construction process was conducted independently of any industrial funding (i.e. pharmaceutical, medical devices). The authors were required to follow the rules of the Grading of Recommendations Assessment, Development and Evaluation (GRADE®) system to guide assessment of quality of evidence. The potential drawbacks of making strong recommendations in the presence of low-quality evidence were emphasised.
methodsThe most recent SFAR and SNFGE guidelines on the management of the patient with severe pancreatitis were published in 2001. The literature now is sufficient for an update. The committee studied 14 questions within 3 fields. Each question was formulated in a PICO (Patients Intervention Comparison Outcome) format and the relevant evidence profiles were produced. The literature review and recommendations were made according to the GRADE® methodology.
resultsThe experts' synthesis work and their application of the GRADE® method resulted in 24 recommendations. Among the formalised recommendations, 8 have high levels of evidence (GRADE 1+/-) and 12 have moderate levels of evidence (GRADE 2+/-). For 4 recommendations, the GRADE method could not be applied, resulting in expert opinions. Four questions did not find any response in the literature. After one round of scoring, strong agreement was reached for all the recommendations.
conclusionsThere was strong agreement among experts for 24 recommendations to improve practices for the management of intensive care patients with severe acute pancreatitis.
Indexed as
Identifiers
35636304What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.