Evidence map›Paper›PMID 35635215›Full record

ArticleMedical physics2022

Technical note: Low-cost MR-compatible pneumatic respiratory organ motion simulator for the development of MR-guided thermal therapy.

Kisoo Kim, Peter Jones, Chris Diederich, Eugene Ozhinsky

Abstract read
In one paragraph

Article in Medical physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Motion-robust, multi-slice, real-time MR thermometry for MR-guided thermal therapy in abdominal organs.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kisoo KimDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, USA.
Peter JonesDepartment of Radiation Oncology, University of California San Francisco, San Francisco, California, USA.
Chris DiederichDepartment of Radiation Oncology, University of California San Francisco, San Francisco, California, USA.
Eugene OzhinskyDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, USA.

Funding

Deployable Ultrasound Applicators for MRI Guided Thermal Therapy of Pancreatic CancerR01EB025990 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DIEDERICH, CHRIS JOHN · 2018 to 2022
$2.2M
Development of Methods for Precise MR-guided Hyperthermia Delivery for Targeted Cancer TherapiesR21EB026018 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI OZHINSKY, EUGENE · 2019 to 2021
$603k
Deployable Endoluminal Ultrasound Phased Array for Precision Treatment of Pancreatic CancerR21CA230120 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DIEDERICH, CHRIS JOHN · 2018 to 2019
$377k
NCI NIH HHS R21 CA230120NIBIB NIH HHS R01 EB025990NIBIB NIH HHS R21 EB026018NIH HHS R01EB025990NIH HHS R21CA230120NIH HHS R21EB026018
6 · The paper itself

Abstract

backgroundIn magnetic resonance (MR)-guided thermal therapy, respiratory motion can cause a significant temperature error in MR thermometry and reduce the efficiency of the treatment. A respiratory motion simulator is necessary for the development of new MR imaging (MRI) and motion compensation techniques. PURPOSE: The purpose of this study is to develop a low-cost and simple MR-compatible respiratory motion simulator to support proof-of-concept studies of MR monitoring approaches with respiratory-induced abdominal organ motion.

methodsThe phantom motion system integrates pneumatic control via an actuator subsystem located outside the MRI and coupled via plastic tubing to a compressible bag for distention and retraction within the MRI safe motion subsystem and phantom positioned within the MRI scanner. Performance of the respiratory motion simulator was evaluated with a real-time gradient echo MRI pulse sequence.

resultsThe motion simulator can produce respiratory rates in the range of 8-16 breaths/min. Our experiments showed the consistent periodic motion of the phantom during MRI acquisition in the range of 3.7-9 mm with 16 breaths/min. The operation of the simulator did not cause interference with MRI acquisition.

conclusionsIn this study, we have demonstrated the ability of the motion simulator to generate controlled respiratory motion of a phantom. The low-cost MR-compatible respiratory motion simulator can be easily constructed from off-the-shelf and 3D-printed parts based on open-source 3D models and instructions. This could lower the barriers to the development of new MRI techniques with motion compensation.

Indexed as

Magnetic Resonance ImagingOrgan MotionMagnetic Resonance SpectroscopyMotionPhantoms, Imagingabdomenmotion simulatorMR-compatibleMRgFUSrespiratory motion

Identifiers

PMID35635215
PMCPMC9288488

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.