ArticleImmunity, inflammation and disease2022
Symptomatic femoral head necrosis in patients with rheumatoid arthritis: A retrospective case-control study.
Article in Immunity, inflammation and disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed, 6 citations in OpenAlex.
- Laboratory indices in patients with osteonecrosis of the femoral head: a retrospective comparative study.Journal of orthopaedic surgery and research · 2023Article
- Symptomatic femoral head necrosis in patients with rheumatoid arthritis: A retrospective case-control study.Immunity, inflammation and disease · 2022Article
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6 authors at 1 institution in 1 country.
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Abstract
objectiveWe conducted a retrospective case-control study to investigate the risk factors for osteonecrosis of the femoral head (ONFH) in rheumatoid arthritis (RA) patients.
methodsThe clinical data of patients diagnosed with RA at Fujian Provincial Hospital from January 2013 to December 2020 were retrospectively collected and evaluated. Twenty-two patients with ONFH were identified. Eighty-eight age-, sex-, and disease duration-matched RA patients without symptomatic ONFH were randomly selected as controls in a ratio of 1:4. Logistic regression analysis was used to analyze the risk factors.
resultsThe anticardiolipin (ACL)-immunoglobulin G (IgG) concentration, clinical disease activity index, simplified disease activity index, incidence of hyperlipidemia in the case group were higher than those in the control group. Multivariate logistic regression analysis did not find the independent risk factor in ONFH patients with RA.
conclusionThe pathogenesis of ONFH in RA is related to many factors such as ACL IgG, disease activity index, and hyperlipidemia. While, we went to great lengths to explore the relationship between antiphospholipid antibodies and ONFH, but it plays a very small role.
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