Evidence map›Paper›PMID 35634917›Full record

Observational studyThe Journal of international medical research2022

Programmed multi-level ventilation in COVID-19-related acute respiratory distress syndrome: a multi-center retrospective observational study.

Filip Depta, Pavol Török, Andrew G Miller, Peter Firment, Jozef Leškanič, Adam Porubän, Pavol Halaš, Stanislav Mandinec, Vladimír Filka, Henryk Zajac and 2 more

Open access · goldAbstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in The Journal of international medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 3 countries.

Filip DeptaDepartment of Anesthesiology and Intensive Care, East Slovak Institute of Cardiovascular Diseases, Slovakia.ORCID https://orcid.org/0000-0002-2854-0450
Pavol TörökDepartment of Anesthesiology and Intensive Care, East Slovak Institute of Cardiovascular Diseases, Slovakia.
Andrew G MillerRespiratory Care Services, Duke University Medical Center, Durham, North Carolina, USA.
Peter FirmentDepartment of Anesthesiology and Intensive Care, FN Hospital J. A. Reimana Prešov, Slovakia.
Jozef LeškaničDepartment of Anesthesiology and Intensive Care, Sv. Jakuba Hospital, Bardejov, Slovakia.
Adam PorubänDepartment of Anesthesiology and Intensive Care, Liptov Hospital, Liptovský Mikuláš, Slovakia.
Pavol HalašDepartment of Anesthesiology and Intensive Care, Hospital Myjava, Slovakia.
Stanislav MandinecDepartment of Anesthesiology and Intensive Care, Faculty Hospital, Trenčín, Slovakia.
Vladimír FilkaDepartment of Anesthesiology and Intensive Care, L. Pasteur University Hospital, Košice, Slovakia.
Henryk ZajacDepartment of Anesthesiology and Intensive Care, AGEL Hospital, Krompachy, Slovakia.
Michael A GentileIPM Chirana Inc., Durham, North Carolina, USA.
Marko ZdravkovicDepartment of Anesthesiology, Intensive Care and Pain Management, University Medical Centre Maribor, Maribor, Slovenia.
University of Pavol Jozef Šafárik · SKDuke University · USSlovak Caves Administration · SKUniversity Clinical Centre Maribor · SIUniversity of Prešov · SKUniverzitná Nemocnica Louisa Pasteura · SKVysoká škola manažmentu, City University of Seattle · SK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe evaluated pressure-controlled ventilation (PCV) with multiple programmed levels of positive end expiratory pressure (programmed multi-level ventilation; PMLV) in patients with coronavirus disease 2019 (COVID-19)-related acute respiratory distress syndrome (ARDS).

methodsWe conducted a multicenter, retrospective study from November 2020 to February 2021. PMLV was used with PCV in all patients with intensive care admission until improvement in oxygenation (fraction of inspired oxygen [FiO

resultsOf 188 mechanically ventilated patients with COVID-19-related ARDS, we analyzed 60 patients treated with PMLV. Hypoxemia improved in 55 (92%) patients, as measured by the change in partial pressure of oxygen/FiO

conclusionsPMLV appears to be a safe and effective ventilation strategy for improving hypoxemia in patients with COVID-19-related ARDS. Further studies are needed comparing the PMLV mode with the conventional ARDS ventilatory approach.

Indexed as

COVID-19Respiratory Distress SyndromeHumansHypoxiaOxygenRetrospective StudiesOxygenAcute respiratory distress syndromecoronavirus disease 2019intensive caremechanical ventilationprogrammed multi-level ventilationrespiratory failure

Identifiers

PMID35634917
PMCPMC9158417
OpenAlexW4281623036

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.