Evidence map›Paper›PMID 35634798›Full record

ArticleMacromolecular bioscience2022

Silk-Elastin-Like-Protein/Graphene-Oxide Composites for Dynamic Electronic Biomaterials.

Zaira Martín-Moldes, Quintin Spey, Tiara Bhatacharya, David L Kaplan

Open access · greenAbstract read
In one paragraph

Article in Macromolecular bioscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Spontaneous Self-Organized Order Emerging From Intrinsically Disordered Protein Polymers.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Zaira Martín-MoldesDepartment of Biomedical Engineering, Tufts University, 4 Colby Street, Medford, MA, 02155, USA.
Quintin SpeyDepartment of Biomedical Engineering, Tufts University, 4 Colby Street, Medford, MA, 02155, USA.
Tiara BhatacharyaDepartment of Biomedical Engineering, Tufts University, 4 Colby Street, Medford, MA, 02155, USA.
David L KaplanDepartment of Biomedical Engineering, Tufts University, 4 Colby Street, Medford, MA, 02155, USA.ORCID 0000-0002-9245-7774
Tufts University · US

Funding

Tissue Engineering Resource Center: TTDP41EB027062 · NIBIB · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Gordana Vunjak-Novakovic · 2019 to 2026
$12.6M
NIBIB NIH HHS P41 EB027062
6 · The paper itself

Abstract

Genetically engineered silk-elastin-like-proteins (SELPs) synthesized with the combination of silk and elastin domains are bioengineered to also contain a graphene oxide (GO) binding domain. The conductivity and mechanical stability of graphene, combined with SELP-specific graphene interfaces are pursued as dynamic hybrid materials, toward biomaterial-based electronic switches. The resulting bioengineered proteins with added GO demonstrate cytocompatibility and conductivity that could be modulated by changing hydrogel size in response to temperature due to the SELP chemistry. Upon increased temperature, the gels coalesce and contract, providing sufficient condensed spacing to facilitate conductivity via the graphene domains, a feature that is lost at lower temperatures with the more expanded hydrogels. This thermally induced contraction-expansion is reversible and cyclable, providing an "on-off" conductive switch driven by temperature-driven hydrogel shape-change.

Indexed as

GraphiteSilkBiocompatible MaterialsElastinElectronicsHydrogelsOxidesBiocompatible MaterialsElastingraphene oxideGraphiteHydrogelsOxidesSilkelectronicsgraphene oxidehydrogelsilk-elastin-like-proteinsstimuli-responsive

Identifiers

PMID35634798
PMCPMC9391278
OpenAlexW4281760391

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.