Evidence map›Paper›PMID 35634756›Full record

ReviewLetters in applied microbiology2022

The denture microbiome in health and disease: an exploration of a unique community.

J Redfern, L Tosheva, S Malic, M Butcher, G Ramage, J Verran

Open access · hybridAbstract readReview
In one paragraph

Review in Letters in applied microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  9. Fungal biofilms in human health and disease.Nature reviews. Microbiology · 2025
    Review
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  15. Current issues in molecular biology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

J RedfernDepartment of Natural Sciences, Faculty of Science and Engineering, Manchester Metropolitan University, Manchester, UK.ORCID https://orcid.org/0000-0003-0958-683X
L ToshevaDepartment of Natural Sciences, Faculty of Science and Engineering, Manchester Metropolitan University, Manchester, UK.
S MalicDepartment of Life Sciences, Faculty of Science and Engineering, Manchester Metropolitan University, Manchester, UK.
M ButcherDepartment of Oral Sciences, Glasgow Dental School, School of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, UK.
G RamageDepartment of Oral Sciences, Glasgow Dental School, School of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, UK.
J VerranDepartment of Life Sciences, Faculty of Science and Engineering, Manchester Metropolitan University, Manchester, UK.
Manchester Metropolitan University · GBUniversity of Glasgow · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The United Nations suggests the global population of denture wearers (an artificial device that acts as a replacement for teeth) is likely to rise significantly by the year 2050. Dentures become colonized by microbial biofilms, the composition of which is influenced by complex factors such as patient's age and health, and the nature of the denture material. Since colonization (and subsequent biofilm formation) by some micro-organisms can significantly impact the health of the denture wearer, the study of denture microbiology has long been of interest to researchers. The specific local and systemic health risks of denture plaque are different from those of dental plaque, particularly with respect to the presence of the opportunist pathogen Candida albicans and various other nonoral opportunists. Here, we reflect on advancements in our understanding of the relationship between micro-organisms, dentures, and the host, and highlight how our growing knowledge of the microbiome, biofilms, and novel antimicrobial technologies may better inform diagnosis, treatment, and prevention of denture-associated infections, thereby enhancing the quality and longevity of denture wearers.

Indexed as

Anti-Infective AgentsMicrobiotaBiofilmsCandida albicansDenturesHumansAnti-Infective Agentsantimicrobialsbiocontrolbiofilmsdiseasesdiversity

Identifiers

PMID35634756
PMCPMC9546486
OpenAlexW4281673213

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.