Evidence map›Paper›PMID 35634726›Full record

ArticlePharmaceutical biology2022

Antiperspirant effects and mechanism investigation of Mulisan decoction in rats based on plasma metabolomics.

Shan-Peng Ma, Wei-Ping Ma, Shi-Ning Yin, Xiang-Yue Chen, Xiao-Qing Ma, Bao-Hong Wei, Jing-Guang Lu, Hong-Bing Liu

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Shan-Peng MaKey Laboratory of Marine Drugs, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.ORCID 0000-0003-2451-6557
Wei-Ping MaKey Laboratory of Marine Drugs, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.
Shi-Ning YinQingdao Institute for Food and Drug Control, Qingdao, China.
Xiang-Yue ChenKey Laboratory of Marine Drugs, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.
Xiao-Qing MaKey Laboratory of Marine Drugs, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.
Bao-Hong WeiKey Laboratory of Marine Drugs, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.
Jing-Guang LuQingdao Institute for Food and Drug Control, Qingdao, China.
Hong-Bing LiuKey Laboratory of Marine Drugs, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.ORCID 0000-0001-5530-1490
Ocean University of China · CNQingdao Municipal Center for Disease Control and Prevention · CNQingdao National Laboratory for Marine Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextMulisan decoction (MLS) is a classic formula of traditional Chinese medicine for treating hyperhidrosis. The mechanism remains unclear.

objectiveTo investigate the antiperspirant effect and underlying mechanisms of MLS. MATERIALS AND

methodsFifty rats were divided into control, model, and three doses of MLS intervention groups (

resultsRats treated with MLS presented a significant decrease in sweat point numbers (13.5%), increase in body weight (13.2%), and promotion in the balance of Th1/Th2 cytokine ratio

conclusionsMLS demonstrated a good antiperspirant effect and metabolism improvement. These findings inspire more clinical study validation on immune improvement and antiperspirant effect.

Indexed as

AntiperspirantsHyperhidrosisMedicine, Chinese TraditionalAnimalsInterleukin-2Interleukin-6MetabolomicsRatsTumor Necrosis Factor-alphaAntiperspirantsInterleukin-2Interleukin-6Tumor Necrosis Factor-alphahyperhidrosismetabolic mechanismpharmacodynamicsTraditional Chinese medicine

Identifiers

PMID35634726
PMCPMC9154783
OpenAlexW4281610123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.