Evidence map›Paper›PMID 35634707›Full record

ArticleGut microbes

Interaction effect between NAFLD severity and high carbohydrate diet on gut microbiome alteration and hepatic

Hyena Kang, Hyun Ju You, Giljae Lee, Seung Hyun Lee, Taekyeong Yoo, Murim Choi, Sae Kyung Joo, Jeong Hwan Park, Mee Soo Chang, Dong Hyeon Lee and 3 more

Open access · goldAbstract read
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
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  3. Nutrients · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 3 countries.

Hyena KangDepartment of Environmental Health Sciences, Graduate School of Public Health, Seoul National University, Republic of Korea.
Hyun Ju YouDepartment of Environmental Health Sciences, Graduate School of Public Health, Seoul National University, Republic of Korea.
Giljae LeeDepartment of Environmental Health Sciences, Graduate School of Public Health, Seoul National University, Republic of Korea.
Seung Hyun LeeDepartment of Environmental Health Sciences, Graduate School of Public Health, Seoul National University, Republic of Korea.
Taekyeong YooDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.
Murim ChoiDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.
Sae Kyung JooDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul Metropolitan Government Boramae Medical Center, Seoul, Republic of Korea.
Jeong Hwan ParkDepartment of Pathology, Seoul National University College of Medicine, Seoul Metropolitan Government Boramae Medical Center, Seoul, Republic of Korea.
Mee Soo ChangDepartment of Pathology, Seoul National University College of Medicine, Seoul Metropolitan Government Boramae Medical Center, Seoul, Republic of Korea.
Dong Hyeon LeeDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul Metropolitan Government Boramae Medical Center, Seoul, Republic of Korea.ORCID 0000-0003-2044-6854
Won KimDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul Metropolitan Government Boramae Medical Center, Seoul, Republic of Korea.ORCID 0000-0002-2926-1007
GwangPyo KoDepartment of Environmental Health Sciences, Graduate School of Public Health, Seoul National University, Republic of Korea.ORCID 0000-0002-0524-2194
Innovative Target Exploration of NAFLD (ITEN) consortium
Seoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nonalcoholic fatty liver disease (NAFLD) is associated with high carbohydrate (HC) intake. We investigated whether the relationship between carbohydrate intake and NAFLD is mediated by interactions between gut microbial modulation, impaired insulin response, and hepatic

Indexed as

Gastrointestinal MicrobiomeNon-alcoholic Fatty Liver DiseaseDietDietary CarbohydratesHumansLipogenesisRNA, Ribosomal, 16SDietary CarbohydratesRNA, Ribosomal, 16Sde novo lipogenesisgut microbiomehigh carbohydrate dietliver transcriptomeNonalcoholic fatty liver disease

Identifiers

PMID35634707
PMCPMC9154801
OpenAlexW4281766805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.