Evidence map›Paper›PMID 35634508›Full record

ArticleFrontiers in endocrinology2022

Increased Risk for Respiratory Complications in Male Extremely Preterm Infants: A Propensity Score Matching Study.

Zhiwen Su, Lili Lin, Xi Fan, Chunhong Jia, Bijun Shi, Xiaoxia Huang, Jianwei Wei, Qiliang Cui, Fan Wu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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  14. Remarkable sex-specific differences at single-cell resolution in neonatal hyperoxic lung injury.American journal of physiology. Lung cellular and molecular physiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Zhiwen SuDepartment of Pediatrics, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Lili LinDepartment of Pediatrics, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Xi FanDepartment of Pediatrics, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Chunhong JiaDepartment of Pediatrics, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Bijun ShiDepartment of Pediatrics, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Xiaoxia HuangDepartment of Pediatrics, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Jianwei WeiDepartment of Pediatrics, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Qiliang CuiDepartment of Pediatrics, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Fan WuDepartment of Pediatrics, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Third Affiliated Hospital of Guangzhou Medical University · CNGuangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Many factors can affect the clinical outcome of extremely premature infants (EPIs), but the effect of sex is paradoxical. This study used propensity score matching to adjust baseline information to reassess the clinical outcome of EPIs based on sex. Methods: A retrospective analysis was performed on EPIs admitted in the Department of Neonatology of the Third Affiliated Hospital of Guangzhou Medical University from 2011 to 2020. A propensity score matching (PSM) analysis was used to adjust the confounding factors including gestational age, birth weight, 1-minute Apgar score ≤ 3, withholding or withdrawing life-sustaining treatment(WWLST), mechanical ventilation, duration of mechanical ventilation, the mother with advanced age (≥35 years old), complete-course antenatal steroid therapy and hypertensive disorders of pregnancy. The survival rate at discharge and the incidence of major complications were evaluated between the male and female groups. Results: A total of 439 EPIs were included, and 240 (54.7%) infants were males. After matching the nine confounding factors, 148 pairs of infants were finally enrolled. There was no significant difference in the survival rate at discharge, as well as the mortality of activating treatment or WWLST between the two groups (all Conclusions: The male EPIs have a higher risk of respiratory complications than females, particularly at 750 to 999 grams of birth weight.

Indexed as

Bronchopulmonary DysplasiaInfant, Extremely PrematureAdultBirth WeightFemaleHumansInfantInfant, NewbornMalePregnancyPropensity ScoreRetrospective Studiesextremely premature infantsoutcomespropensity score matchingrespiratory complicationssex differences

Identifiers

PMID35634508
PMCPMC9134850
OpenAlexW4280629029

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.