ReviewFrontiers in cellular neuroscience2022
Arterial Calcification and Its Association With Stroke: Implication of Risk, Prognosis, Treatment Response, and Prevention.
Review in Frontiers in cellular neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Breast arterial calcifications on mammography and risk of stroke: a systematic review and meta-analysis.Frontiers in neurologyPooled it
- Association between Cognitive Function and Postoperative Stroke Following Off-Pump Coronary Artery Bypass Grafting.Journal of cardiovascular translational research · 2026Article
- Accuracy of deep learning in the detection of carotid calcifications on cone-beam computed tomography: A systematic review.Imaging science in dentistry · 2026Review
- Association Between Domestic Water Hardness and MRI-Based Measures of Brain Volume: Evidence from the UK Biobank.Health data science · 2026Article
- Dietary index for gut microbiota score is inversely associated with carotid calcified plaque score in ischemic stroke patients.Frontiers in nutrition · 2026Article
- Systemic inflammation and cerebrovascular injury in acute stroke.Revista da Associacao Medica Brasileira (1992) · 2026Article
- An update on pharyngeal assessment by the modified barium swallow.Abdominal radiology (New York) · 2025Review
- Considerations on the Development of Therapeutics in Vascular Calcification.Journal of cardiovascular development and disease · 2025Review
- Involvement of miRNA-204 carried by the exosomes of macrophages in the AT2 receptor-mediated improvement of vascular calcification.Cellular and molecular life sciences : CMLS · 2025Article
- Pictorial Review of Soft Tissue Lesions with Calcification.Diagnostics (Basel, Switzerland) · 2025Review
- Prognostic impact of intracranial arteriosclerosis subtype after endovascular treatment for acute ischaemic stroke.European journal of neurology · 2025Article
- Prevalence and clinical implications of calcification in internal carotid artery stenosis: a retrospective study.BMC neurology · 2024Article
- Stroke Related Brain-Heart Crosstalk: Pathophysiology, Clinical Implications, and Underlying Mechanisms.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- Vascular Calcification: Molecular Networking, Pathological Implications and Translational Opportunities.Biomolecules · 2024Review
- Association between atherosclerosis and the development of multi-organ pathologies.SAGE open medicine · 2024Review
- Vascular calcification: from the perspective of crosstalk.Molecular biomedicine · 2023Review
- Article
- Effect of C1q/TNF-Related Protein 9 on Coronary Artery Calcification: An Observational Study.Journal of cardiovascular development and disease · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stroke is a leading cause of death worldwide. Vascular calcification (VC), defined as deposition of calcium-phosphate complexes in the vessels, is considered as the characteristic of vascular aging. Calcifications at different vessel layers have different implications. Intimal calcification is closely related to atherosclerosis and affects plaque stability, while medial calcification can cause arterial stiffening and reduce compliance. Accumulating evidence suggested that arterial calcifications, including calcifications in the intracranial artery, coronary artery, and carotid artery, are associated with the risk, prognosis, and treatment response of stroke. VC can not only serve as a marker of atherosclerosis, but cause cerebral hemodynamic impairment. In addition, calcifications in large arteries are associated with cerebral small vessel disease. In this review, we summarize the findings of recently published studies focusing on the relationship between large artery calcification and the risk, prognosis, treatment response, and prevention of stroke and also discuss possible mechanisms behind those associations.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.