Evidence map›Paper›PMID 35634454›Full record

ArticleFrontiers in pain research (Lausanne, Switzerland)2022

A Single Dose of Oral Sucrose Is Enough to Control Pain During Venipuncture: A Randomized Controlled Trial.

Maria Elena Cavicchiolo, Marco Daverio, Nadia Battajon, Anna Chiara Frigo, Paola Lago

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pain research (Lausanne, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Maria Elena CavicchioloNeonatal Intensive Care Unit, Department of Woman's and Child's Health, University of Padua, Padua, Italy.
Marco DaverioPaediatric Intensive Care Unit, Department of Woman's and Child's Health, University of Padua, Padua, Italy.
Nadia BattajonNeonatal Intensive Care Unit, Azienda Unità Locale Socio Sanitaria (ULSS) 2 Marca Trevigiana, Treviso, Italy.
Anna Chiara FrigoDepartment of Cardiac-Thoracic-Vascular Sciences and Public Health, University of Padua, Padua, Italy.
Paola LagoNeonatal Intensive Care Unit, Department of Woman's and Child's Health, University of Padua, Padua, Italy.
University of Padua · ITAzienda ULSS 9 TREVISO · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sucrose is effective in reducing pain during minor procedures in neonates. We evaluated whether a second dose of sucrose was more effective than a single dose during venipuncture. We performed a randomised, double-blind, controlled trial at the NICU of Padua Hospital (August 2016-October 2017). We randomised 72 preterm infants undergoing venipuncture for routine test to a control group, which received a single standard dose of sucrose 2' before the procedure and a placebo 30″ after the venipuncture, and an experimental group in which they received two doses of 24% sucrose 2' before and 30″ after the venipuncture. No difference in pain perception was found between the groups at 30″, 60″ and 120″. In conclusion, we do not recommend a second dose of sucrose during venipuncture in prematures.

Indexed as

non-pharmacologic treatmentpainpretermskin breaking proceduressucrose

Identifiers

PMID35634454
PMCPMC9131008
OpenAlexW4280563673

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.