Evidence map›Paper›PMID 35634435›Full record

ArticleDisease markers2022

The Value of SII in Predicting the Mortality of Patients with Heart Failure.

Miao Yuan, Fuxian Ren, Dengfeng Gao

Abstract read
In one paragraph

Article in Disease markers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  12. Heart failure, inflammation and exercise.International journal of biological sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Miao YuanDepartment of Cardiovascular Disease, Second Affiliated Hospital of Xi'an Jiaotong University, 710000, China.
Fuxian RenDepartment of Cardiology, Meishan Brach of the Third Affiliated Hospital, Yanan University School of Medical, 620000, China.ORCID https://orcid.org/0000-0002-6616-5540
Dengfeng GaoDepartment of Cardiovascular Disease, Second Affiliated Hospital of Xi'an Jiaotong University, 710000, China.ORCID https://orcid.org/0000-0003-0458-8852

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The main purpose of this study was to explore the predictive value of the systemic immune inflammation index (SII), a novel clinical marker, in heart failure (HF) patients. Methods: Critically ill patients with HF were identified from the Medical Information Mart for Intensive Care III (MIMIC III) database. Patients were divided into three groups according to tertiles of SII (group 1, group 2, group 3). We used Kaplan-Meier curves and Cox proportional hazards regression models to evaluate the association between the SII and all-cause mortality in HF. Subgroup analysis was used to verify the predictive effect of the SII on mortality. Results: This study included 9107 patients with a diagnosis of HF from the MIMIC III database. After 30, 60, 180, and 365 days of follow-up, 25.60%, 32.10%, 41.30%, and 47.50% of the patients in group 3 had died. Using the Kaplan-Meier curve, we observed that patients with higher SII values had a shorter survival time (log rank Conclusions: SII values could be used as a predictor of prognosis in critically ill patients with HF.

Indexed as

Critical IllnessHeart FailureHumansInflammationPrognosisProportional Hazards Models

Identifiers

PMID35634435
PMCPMC9135558

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.