ArticleFrontiers in nutrition2022
Xylitol-Containing Chewing Gum Reduces Cariogenic and Periodontopathic Bacteria in Dental Plaque-Microbiome Investigation.
Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Effects of Xylitol-laced Sweets on the Accumulation of Dental Plaque : A Systematic Review and Meta-Analysis.International dental journal · 2025Pooled it
- Effect of xylitol on Porphyromonas gingivalis: A systematic review.Clinical and experimental dental research · 2023Pooled it
- Effects of Chewing Gum on Plaque Index: A 3-Dimensional Colorimetric Analysis.Dentistry journal · 2025Article
- Ensemble learning for microbiome-based caries diagnosis: multi-group modeling and biological interpretation from salivary and plaque metagenomic data.BMC oral health · 2025Article
- Effect of Xylitol and Maltitol Chewing Gums on Plaque Reduction and Salivary pH Modulation: A Retrospective Study in Pediatric Patients.Dentistry journal · 2025Article
- Oral health care knowledge among Phenylketonuria patients in the Latvian population.Molecular genetics and metabolism reports · 2024Review
- Oral Microbiome Dynamics in Treated Childhood Caries: A Comparative Study.Life (Basel, Switzerland) · 2024Article
- Efficacy of antimicrobial peptide P113 oral health care products on the reduction of oral bacteria number and dental plaque formation in a randomized clinical assessment.Journal of dental sciences · 2024Article
- Erythritol Can Inhibit the Expression of Senescence Molecules in Mouse Gingival Tissues and Human Gingival Fibroblasts.Nutrients · 2023Article
- Article
- The Treatment Efficiency and Microbiota Analysis ofInternational journal of molecular sciences · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Dental caries and periodontal disease remain the most prevalent oral health problems in the world. Chewing xylitol gum may help reduce the risk of caries and periodontitis for dental health benefits. However, little evidence has shown healthy food estimation by sequencing 16S rDNA in oral microbial communities. This study investigated the clinical effect of xylitol chewing gum on dental plaque accumulation and microbiota composition using the PacBio full-length sequencing platform in 24 young adults ( Results: The results suggested a 20% reduction in dental plaque accumulation ( Conclusion: In conclusion, chewing xylitol gum would benefit cariogenic and periodontal bacterial reduction in the oral cavity, which could help to prevent the diseases related to these bacteria.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.