Evidence map›Paper›PMID 35634303›Full record

ArticleFrontiers in immunology2022

Evaluation of an ImmunoPET Tracer for IL-12 in a Preclinical Model of Inflammatory Immune Responses.

Nerissa T Viola, James E Glassbrook, Jhansi R Kalluri, Justin B Hackett, Madison N Wicker, Joshua Sternberg, Heather M Gibson

Abstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Detection of IL12/23p40 via PET Visualizes Inflammatory Bowel Disease.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nerissa T ViolaDepartment of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI, United States.
James E GlassbrookDepartment of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI, United States.
Jhansi R KalluriDepartment of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI, United States.
Justin B HackettCancer Biology Graduate Program, School of Medicine, Wayne State University, Detroit, MI, United States.
Madison N WickerDepartment of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI, United States.
Joshua SternbergDepartment of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI, United States.
Heather M GibsonDepartment of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI, United States.

Funding

Tumor Biology and Microenvironment (Program 1)P30CA022453 · NCI · WAYNE STATE UNIVERSITY · PI Julie Lynn Boerner · 1985 to 2026
$68.4M
TRAINING PROGRAM IN THE BIOLOGY OF CANCERT32CA009531 · NCI · WAYNE STATE UNIVERSITY · PI Larry H Matherly · 1985 to 2026
$5.3M
Delineating Functional Immunity via Image-Guided PETR37CA220482 · NCI · WAYNE STATE UNIVERSITY · PI GIBSON, HEATHER MARIE, VIOLA, NERISSA THERESE · 2018 to 2024
$3.9M
NCI NIH HHS P30 CA022453NCI NIH HHS R37 CA220482NCI NIH HHS T32 CA009531
6 · The paper itself

Abstract

The immune cytokine interleukin-12 (IL-12) is involved in cancer initiation and progression, autoimmunity, as well as graft versus host disease. The ability to monitor IL-12

Indexed as

Granulocyte-Macrophage Colony-Stimulating FactorInterleukin-12AdenoviridaeAnimalsCytokinesHumansImmunityLipopolysaccharidesMiceMice, Inbred BALB CTissue DistributionCytokinesGranulocyte-Macrophage Colony-Stimulating FactorInterleukin-12LipopolysaccharidesimmunotherapyinflammationInterleukin-12PET imagingradioactive tracer

Identifiers

PMID35634303
PMCPMC9130849

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.