Evidence map›Paper›PMID 35634283›Full record

ArticleFrontiers in immunology2022

Human Macrophages Exhibit GM-CSF Dependent Restriction of

Abhishek Mishra, Vipul K Singh, Chinnaswamy Jagannath, Selvakumar Subbian, Blanca I Restrepo, Marie-Claire Gauduin, Arshad Khan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. ConcurrentCase reports in infectious diseases · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Host Cell Death and Modulation of Immune Response againstInternational journal of molecular sciences · 2024
    Review
  12. Review
  13. Transcriptional analysis of human peripheral blood mononuclear cells stimulated byFrontiers in cellular and infection microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Abhishek MishraDepartment of Pathology and Genomic Medicine, Houston Methodist Research Institute, Houston, TX, United States.
Vipul K SinghDepartment of Pathology and Genomic Medicine, Houston Methodist Research Institute, Houston, TX, United States.
Chinnaswamy JagannathDepartment of Pathology and Genomic Medicine, Houston Methodist Research Institute, Houston, TX, United States.
Selvakumar SubbianDepartment of Medicine, New Jersey Medical School, Public Health Research Institute, Newark, NJ, United States.
Blanca I RestrepoUniversity of Texas School of Public Health, Brownsville, TX, United States.
Marie-Claire GauduinDisease Intervention and Prevention, Texas Biomedical Research Institute, San Antonio, TX, United States.
Arshad KhanDepartment of Pathology and Genomic Medicine, Houston Methodist Research Institute, Houston, TX, United States.
Houston Methodist · USRutgers New Jersey Medical SchoolTexas Biomedical Research Institute · US

Funding

The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areasP51OD011133 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Larry S. Schlesinger · 2012 to 2026
$129.7M
Viral Testing CoreU42OD010442 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI SHELLEY A COLE · 2012 to 2026
$35.6M
Role of metabolic Me-macrophages in the pathogenesis of tuberculosis during diabetesR21AI144541 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI JAGANNATH, CHINNASWAMY, RESTREPO, BLANCA I · 2020 to 2021
$443k
NIAID NIH HHS R21 AI144541NIH HHS P51 OD011133NIH HHS U42 OD010442
6 · The paper itself

Abstract

GM-CSF is an important cytokine that regulates the proliferation of monocytes/macrophages and its various functions during health and disease. Although growing evidences support the notion that GM-CSF could play a major role in immunity against tuberculosis (TB) infection, the mechanism of GM-CSF mediated protective effect against TB remains largely unknown. Here in this study we examined the secreted levels of GM-CSF by human macrophages from different donors along with the GM-CSF dependent cellular processes that are critical for control of

Indexed as

Granulocyte-Macrophage Colony-Stimulating FactorMacrophagesMycobacterium tuberculosisTuberculosisCell DifferentiationCytokinesHumansCytokinesGranulocyte-Macrophage Colony-Stimulating Factorantigen presentationautophagycell deathcellular metabolismgranulocyte macrophage colony-stimulating factormacrophagesMycobacterium tuberculosistuberculosis

Identifiers

PMID35634283
PMCPMC9134823
OpenAlexW4280566384

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.