Evidence map›Paper›PMID 35634277›Full record

ArticleFrontiers in immunology2022

CCR4 and CCR5 Involvement in Monocyte-Derived Macrophage Migration in Neuroinflammation.

Jong Youl Kim, Jiwon Kim, Meiying Huang, Renée Kosonen, Jong Eun Lee

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jong Youl KimDepartment of Anatomy, Yonsei University College of Medicine, Seoul, South Korea.
Jiwon KimDepartment of Anatomy, Yonsei University College of Medicine, Seoul, South Korea.
Meiying HuangDepartment of Anatomy, Yonsei University College of Medicine, Seoul, South Korea.
Renée KosonenDepartment of Anatomy, Yonsei University College of Medicine, Seoul, South Korea.
Jong Eun LeeDepartment of Anatomy, Yonsei University College of Medicine, Seoul, South Korea.
Yonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microglia, resident macrophages in the brain, play major roles in neuroinflammation after an acute many neurological diseases, including stroke. Our recent animal stroke model showed that interleukin (IL)-4 and IL-13 released by microglia are converted into monocyte-derived macrophages. However, the correlation with the migration mechanism of these cells is still unclear. This study aimed to clarify the effect of these cells on their migration and to identify potential targets that influence neuroinflammatory conditions. Inflammatory conditions were induced by lipopolysaccharide (LPS) treatment in

Indexed as

LipopolysaccharidesStrokeAnimalsChemokinesDisease Models, AnimalMacrophagesNeuroinflammatory DiseasesChemokinesLipopolysaccharidesCCR4CCR5microgliamonocyte-derived macrophageneuroinflammation

Identifiers

PMID35634277
PMCPMC9133420
OpenAlexW4280597076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.