Evidence map›Paper›PMID 35634155›Full record

ArticleFrontiers in physiology2022

Effects of Exogenous Transferrin on the Regulation of Iron Metabolism and Erythropoiesis in Iron Deficiency With or Without Anemia.

Yihang Li, Ian Miller, Princy Prasad, Nisha Ajit George, Nermi L Parrow, Robert E Fleming

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yihang LiDepartment of Pediatrics, Saint Louis University School of Medicine, St. Louis, MO, United States.
Ian MillerDepartment of Pediatrics, Saint Louis University School of Medicine, St. Louis, MO, United States.
Princy PrasadDepartment of Pediatrics, Saint Louis University School of Medicine, St. Louis, MO, United States.
Nisha Ajit GeorgeDepartment of Pediatrics, Saint Louis University School of Medicine, St. Louis, MO, United States.
Nermi L ParrowDepartment of Pediatrics, Saint Louis University School of Medicine, St. Louis, MO, United States.
Robert E FlemingDepartment of Pediatrics, Saint Louis University School of Medicine, St. Louis, MO, United States.
Saint Louis University · US

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Regulatory Role of Transferrin in Erythropoiesis and Iron MetabolismR01DK095112 · NIDDK · SAINT LOUIS UNIVERSITY · PI Robert E Fleming, Yelena Ginzburg · 2012 to 2026
$5.4M
NCATS NIH HHS UL1 TR002345NIDDK NIH HHS R01 DK095112
6 · The paper itself

Abstract

Erythropoietic response is controlled not only by erythropoietin but also by iron. In addition to its role in iron delivery, transferrin also functions as a signaling molecule, with effects on both iron homeostasis and erythropoiesis. We investigated hematologic parameters, iron status and expression of key proteins, including the hepatic iron regulatory protein hepcidin and the suppressive erythroid factor

Indexed as

anemiaerythroferroneerythropoiesiserythropoietinhepcidinironiron deficiencytransferrin

Identifiers

PMID35634155
PMCPMC9132588
OpenAlexW4280560416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.