Evidence map›Paper›PMID 35633985›Full record

ArticleAvicenna journal of medical biotechnology

Association of Aberrant Promoter Methylation Changes in the Suppressor of Cytokine Signaling 3

Golshid Sanati, Davood Jafari, Mehrdad Noruzinia, Naser Ebrahimi Daryani, Mohammad Ahmadvand, Shahram Teimourian, Nima Rezaei

Open access · greenAbstract read
In one paragraph

Article in Avicenna journal of medical biotechnology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Frontiers in immunology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Golshid SanatiDepartment of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Davood JafariDepartment of Immunology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Mehrdad NoruziniaDepartment of Medical Genetics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Naser Ebrahimi DaryaniDepartment of Internal Medicine, Division of Gastroenterology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad AhmadvandDepartment of Medical Genetics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Shahram TeimourianDepartment of Genetics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Nima RezaeiDepartment of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Tarbiat Modares University · IRTehran University of Medical Sciences · IRIran University of Medical Sciences · IRResearch Network (United States) · USZanjan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Growing evidence supports that changes in the methylation state of Inflammatory Bowel Disease (IBD)-associated genes could significantly alter levels of gene expression, potentially contributing to disease onset and progression. We supposed that alterations in DNA methylation status at promoter region within the suppressor of cytokine signaling 3 Methods: DNA methylation status in the promoter region of the human Results: Based on methylation assay data profiling, we found that patients with CD showed a higher degree of methylation of the Conclusion: The data presented here demonstrate that aberrant methylation of the CpG islands within promoter regions of

Indexed as

Crohn's diseaseDNA methylationEpigeneticsImmune regulationSOCS3

Identifiers

PMID35633985
PMCPMC9077662
OpenAlexW4221044556

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.