Evidence map›Paper›PMID 35633909›Full record

ReviewWorld journal of gastroenterology2022

Current status and future of targeted peptide receptor radionuclide positron emission tomography imaging and therapy of gastroenteropancreatic-neuroendocrine tumors.

Neil Grey, Michael Silosky, Christopher H Lieu, Bennett B Chin

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Neil GreyRadiology-Nuclear Medicine, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045, United States.
Michael SiloskyDepartment of Radiology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045, United States.
Christopher H LieuMedical Oncology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045, United States.
Bennett B ChinDepartment of Radiology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045, United States. bennett.chin@cuanschutz.edu.
University of Colorado Anschutz Medical Campus · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Theranostics is the highly targeted molecular imaging and therapy of tumors. Targeted peptide receptor radionuclide therapy has taken the lead in demonstrating the safety and effectiveness of this molecular approach to treating cancers. Metastatic, well-differentiated gastroenteropancreatic neuroendocrine tumors may be most effectively imaged and treated with DOTATATE ligands. We review the current practice, safety, advantages, and limitations of DOTATATE based theranostics. Finally, we briefly describe the exciting new areas of development and future directions of gastroenteropancreatic neuroendocrine tumor theranostics.

Indexed as

Neuroendocrine TumorsGallium RadioisotopesHumansIntestinal NeoplasmsPancreatic NeoplasmsPositron-Emission TomographyPositron Emission Tomography Computed TomographyRadioisotopesRadionuclide ImagingRadiopharmaceuticalsReceptors, PeptideStomach Neoplasmscopper dotatate CU-64Gallium RadioisotopesRadioisotopesRadiopharmaceuticalsReceptors, Peptide177Lu DOTATATE68Ga DOTATATEDOTATATEGastroenteropancreatic neuroendocrine tumorsReviewTheranostics

Identifiers

PMID35633909
PMCPMC9099199
OpenAlexW4225011188

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.