ArticleOxidative medicine and cellular longevity2022
Monocyte-to-Lymphocyte Ratio Was an Independent Factor of the Severity of Spinal Tuberculosis.
Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Study on the pathological diagnostic value of spinal tuberculosis lesions with different submitting methods and tissue types.Journal of orthopaedic surgery and research · 2026Article
- LASSO regression-based machine learning model for differentiating spinal tuberculosis, pyogenic spondylitis, and endplate osteochondritis: development and clinical application.Frontiers in cellular and infection microbiology · 2026Article
- Incremental value of quantitative SPECT/CT integrated parameters in a multimodal machine-learning model for differentiating spinal tuberculosis from pyogenic spondylitis.Frontiers in cellular and infection microbiology · 2026Article
- Two-centers machine learning analysis for predicting acid-fast bacilli results in tuberculosis sputum tests.Journal of clinical tuberculosis and other mycobacterial diseases · 2025Article
- Clinical Utility of Monocyte-to-Lymphocyte Ratio and Prognostic Nutritional Index in Diagnosing Smear-Negative Pulmonary Tuberculosis with Negative IGRA Results.Infection and drug resistance · 2025Article
- Inflammatory Markers as Predictors of Diabetes Mellitus in Patients with Pulmonary Tuberculosis: A Retrospective Analysis of Hematological Parameters and Clinical Features.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- A novel circulating miRNA panel for early differential diagnosis of pulmonary tuberculosis from lung cancer with similar radiographic presentations.Frontiers in medicine · 2025Article
- Unlocking the Diagnostic Potential: A Systematic Review of Biomarkers in Spinal Tuberculosis.Journal of clinical medicine · 2024Review
- Prediction model for spinal cord injury in spinal tuberculosis patients using multiple machine learning algorithms: a multicentric study.Scientific reports · 2024Article
- Development and validation of a diagnostic model to differentiate spinal tuberculosis from pyogenic spondylitis by combining multiple machine learning algorithms.Biomolecules & biomedicine · 2024Article
- Inflammatory Profile Assessment in a Highly Selected Athyreotic Population Undergoing Controlled and Standardized Hypothyroidism.Biomedicines · 2024Article
- Association Between Indices of Peripheral Blood Inflammation and Cavitary Pulmonary Tuberculosis.International journal of general medicine · 2024Article
- Assessing the effects of diabetes mellitus on the monocyte-to-lymphocyte ratio and the QuantiFERON-TB gold plus assays for tuberculosis treatment monitoring: a prospective cohort study.Frontiers in immunology · 2024Article
- Integrating systemic immune-inflammation index, fibrinogen, and T-SPOT.TB for precision distinction of active pulmonary tuberculosis in the era of mycobacterial disease research.Frontiers in microbiology · 2024Article
- Diagnostic value of the neutrophil lymphocyte ratio in discrimination between tuberculosis and bacterial community acquired pneumonia: AJournal of clinical tuberculosis and other mycobacterial diseases · 2023Review
- Comparative Study on the Efficacy of Two Perioperative Chemotherapy Regimens for Lumbar Brucellosis.Drug design, development and therapy · 2023Article
- U-Shaped Association Between Monocyte-Lymphocyte Ratio and Risk of Cardiac Conduction Block.Journal of inflammation research · 2023Article
- The survival analysis of rifampicin/multidrug-resistant tuberculosis patients based on the levels of inflammatory biomarkers: a retrospective cohort study.Frontiers in cellular and infection microbiology · 2023Article
- Identification of spinal tuberculosis subphenotypes using routine clinical data: a study based on unsupervised machine learning.Annals of medicine · 2023Article
- Monocyte-to-lymphocyte ratio is significantly associated with positive QuantiFERON-TB Gold-In-Tube and adult survival: an observational study.Scientific reports · 2022Observational
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20 authors.
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Abstract
Purpose: The purpose was to explore the relationship between monocyte-to-lymphocyte ratio (MLR) and the severity of spinal tuberculosis. Methods: A total of 1,000 clinical cases were collected, including 496 cases of spinal tuberculosis and 504 cases of nonspinal tuberculosis. Laboratory blood results were collected, including C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), white blood cells (WBC), hemoglobin (HGB), platelets (PLT), neutrophil count, percentage of neutrophils, lymphocyte count, percentage of lymphocytes, monocyte count, percentage of monocytes, MLR, platelets -to- monocyte ratio (PMR), platelets -to- lymphocyte ratio (PLR), neutrophil -to- lymphocyte ratio (NLR), and platelets -to- neutrophil ratio (PNR). The statistical parameters analyzed by the Least Absolute Shrinkage and Selection Operator (LASSO) and receiver-operating characteristic (ROC) curves were used to construct the nomogram. The nomogram was assessed by C-index, calibration curve, ROC curve, and decision curve analysis (DCA) curve. Results: The C-index of the nomogram in the training set and external validation set was 0.801 and 0.861, respectively. Similarly, AUC was 0.801 in the former and 0.861 in the latter. The net benefit of the former nomogram ranged from 0.1 to 0.95 and 0.02 to 0.99 in the latter nomogram. Furthermore, there was a correlation between MLR and the severity of spinal tuberculosis. Conclusion: MLR was an independent factor in the diagnosis of spinal tuberculosis and was associated with the severity of spinal tuberculosis. Additionally, MLR may be a predictor of active spinal tuberculosis.
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