Evidence map›Paper›PMID 35633883›Full record

ArticleOxidative medicine and cellular longevity2022

The Endothelial Dysfunction Could Be a Cause of Heart Failure with Preserved Ejection Fraction Development in a Rat Model.

Thomas Dupas, Thomas Pelé, Justine Dhot, Mélanie Burban, Antoine Persello, Virginie Aillerie, Angélique Erraud, Angela Tesse, David Stevant, Angélique Blangy-Letheule and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. The effect of bariatric surgery on patient reported outcomes of heart failure in women: a pilot study.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Vasorelaxant Effect of MoroccanEvidence-based complementary and alternative medicine : eCAM · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Thomas DupasNantes Université, CHU Nantes, CNRS, INSERM, l'institut du thorax, F-44000 Nantes, France.ORCID https://orcid.org/0000-0002-8827-3526
Thomas PeléNantes Université, CHU Nantes, CNRS, INSERM, l'institut du thorax, F-44000 Nantes, France.
Justine DhotNantes Université, CHU Nantes, CNRS, INSERM, l'institut du thorax, F-44000 Nantes, France.
Mélanie BurbanNantes Université, CHU Nantes, CNRS, INSERM, l'institut du thorax, F-44000 Nantes, France.
Antoine PerselloNantes Université, CHU Nantes, CNRS, INSERM, l'institut du thorax, F-44000 Nantes, France.ORCID https://orcid.org/0000-0002-4722-9422
Virginie AillerieNantes Université, CHU Nantes, CNRS, INSERM, l'institut du thorax, F-44000 Nantes, France.
Angélique ErraudNantes Université, CHU Nantes, CNRS, INSERM, l'institut du thorax, F-44000 Nantes, France.
Angela TesseNantes Université, CHU Nantes, CNRS, INSERM, l'institut du thorax, F-44000 Nantes, France.ORCID https://orcid.org/0000-0002-2153-4357
David StevantNantes Université, CHU Nantes, CNRS, INSERM, l'institut du thorax, F-44000 Nantes, France.
Angélique Blangy-LetheuleNantes Université, CHU Nantes, CNRS, INSERM, l'institut du thorax, F-44000 Nantes, France.
Céline MenguyNantes Université, CHU Nantes, CNRS, INSERM, l'institut du thorax, F-44000 Nantes, France.
Vincent SauzeauNantes Université, CHU Nantes, CNRS, INSERM, l'institut du thorax, F-44000 Nantes, France.ORCID https://orcid.org/0000-0002-6187-0312
Michel De WaardNantes Université, CHU Nantes, CNRS, INSERM, l'institut du thorax, F-44000 Nantes, France.ORCID https://orcid.org/0000-0002-2782-9615
Bertrand RozecNantes Université, CHU Nantes, CNRS, INSERM, l'institut du thorax, F-44000 Nantes, France.ORCID https://orcid.org/0000-0002-2226-3982
Chantal GauthierNantes Université, CHU Nantes, CNRS, INSERM, l'institut du thorax, F-44000 Nantes, France.ORCID https://orcid.org/0000-0001-8855-0039
Benjamin LauzierNantes Université, CHU Nantes, CNRS, INSERM, l'institut du thorax, F-44000 Nantes, France.ORCID https://orcid.org/0000-0002-1370-6155
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

50% of patients with heart failure have a preserved ejection fraction (HFpEF). Numerous studies have investigated the pathophysiological mechanisms of HFpEF and have shown that endothelial dysfunction plays an important role in HFpEF. Yet no studies answered whether endothelial dysfunction could be the cause or is the consequence of HFpEF. Recently, we have shown that the endothelial overexpression of human

Indexed as

Heart FailureVascular DiseasesAnimalsAortaHumansRatsStroke VolumeVentricular Function, Left

Identifiers

PMID35633883
PMCPMC9132705
OpenAlexW4280495447

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.