Evidence map›Paper›PMID 35633741›Full record

ArticleWorld journal of orthopedics2022

Anterior vertebral body tethering for idiopathic scoliosis in growing children: A systematic review.

Davide Bizzoca, Andrea Piazzolla, Lorenzo Moretti, Giovanni Vicenti, Biagio Moretti, Giuseppe Solarino

Open access · diamondAbstract read
In one paragraph

Article in World journal of orthopedics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Davide BizzocaUOSD Spinal Deformity Centre, AOU Consorziale Policlinico di Bari, Bari 70124, Italy.
Andrea PiazzollaUOSD Spinal Deformity Centre, AOU Consorziale Policlinico di Bari, Bari 70124, Italy.
Lorenzo MorettiOrthopaedic and Trauma Unit, AUO Consorziale Policlinico di Bari, Bari 70124, Italy.
Giovanni VicentiDepartment of Basic Medical Sciences, Neuroscience and Sense Organs, Orthopaedic and Trauma Unit, University of Bari "Aldo Moro", Bari 70124, Puglia, Italy.
Biagio MorettiDepartment of Basic Medical Sciences, Neuroscience and Sense Organs, Orthopaedic and Trauma Unit, University of Bari "Aldo Moro", Bari 70124, Puglia, Italy.
Giuseppe SolarinoDepartment of Basic Medical Sciences, Neuroscience and Sense Organs, Orthopaedic and Trauma Unit, University of Bari "Aldo Moro", Bari 70124, Puglia, Italy. giuseppe.solarino@uniba.it.
Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari · ITUniversity of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe management of idiopathic scoliosis (IS) in skeletally immature patients should aim at three-dimensional deformity correction, without compromising spinal and chest growth. In 2019, the US Food and Drug Administration approved the first instrumentation system for anterior vertebral body tethering (AVBT), under a Humanitarian Device Exception, for skeletally immature patients with curves having a Cobb angle between 35° and 65°.

aimTo summarize current evidence about the efficacy and safety of AVBT in the management of IS in skeletally immature patients.

methodsFrom January 2014 to January 2021, Ovid Medline, Embase, Cochrane Library, Scopus, Web of Science, Google Scholar and PubMed were searched to identify relevant studies. The methodological quality of the studies was evaluated and relevant data were extracted.

resultsSeven clinical trials recruiting 163 patients were included in the present review. Five studies out of seven were classified as high quality, whereas the remaining two studies were classified as moderate quality. A total of 151 of 163 AVBT procedures were performed in the thoracic spine, and the remaining 12 tethering in the lumbar spine. Only 117 of 163 (71.8%) patients had a nonprogressive curve at skeletal maturity. Twenty-three of 163 (14.11%) patients required unplanned revision surgery within the follow-up period. Conversion to posterior spinal fusion (PSF) was performed in 18 of 163 (11%) patients.

conclusionAVBT is a promising growth-friendly technique for treatment of IS in growing patients. However, it has moderate success and perioperative complications, revision and conversion to PSF.

Indexed as

Anterior spinal instrumentationAnterior vertebral body tetheringCurve correctionGrowing spineGrowth-friendly spinal implantsIdiopathic scoliosisPaediatric spineSkeletally immature patientsSpinal growth modulation

Identifiers

PMID35633741
PMCPMC9125003
OpenAlexW4280606202

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.