Evidence map›Paper›PMID 35633703›Full record

ReviewFrontiers in microbiology2022

New Developments and Opportunities of Microbiota in Treating Breast Cancers.

Zihui Meng, Zixuan Ye, Pengrong Zhu, Jianguo Zhu, Shuguang Fang, Tianzhu Qiu, Yanan Li, Lijuan Meng

Abstract readReview
In one paragraph

Review in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Gut Microbiota and Extraintestinal Cancers: Mechanistic Insights and Microbiome-Targeted Interventions.JGH open : an open access journal of gastroenterology and hepatology · 2026
    Review
  2. Review
  3. Review
  4. Effects of gut microbiota in breast cancer.Frontiers in oncology · 2025
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. In Silico and in vitro Characterization ofIranian journal of pharmaceutical research : IJPR
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zihui MengSchool of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing, China.
Zixuan YeSchool of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing, China.
Pengrong ZhuSchool of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing, China.
Jianguo ZhuWecare Probiotics Co., Ltd., Suzhou, China.
Shuguang FangWecare Probiotics Co., Ltd., Suzhou, China.
Tianzhu QiuDepartment of Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yanan LiSchool of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing, China.
Lijuan MengDepartment of Geriatric Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the prevalence of breast cancer (BC), over half of BC cases are unrelated to known risk factors, which highlights the importance of uncovering more cancer-related factors. Currently, the microbiota has been proven to be a potent modulator of the tumor environment in BC, which regulates the immune balance in tumor-related networks. Through a large amount of data accumulation, the microbiota has shown many possibilities to reveal more insights into the development or control of BC. To expand the potential benefits of patients with BC, this study discusses the distribution profile and the effect mechanism of BC-related microbiota on tumors and further discusses its impact on different tumor therapies. Finally, we summarize the possibility of targeting microbiological therapies to improve BC treatment or in combination with other therapies.

Indexed as

breast cancerimmunemicrobiotatargeted therapytumor environment

Identifiers

PMID35633703
PMCPMC9134200

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.