ArticleJournal of clinical research in pediatric endocrinology2022
Has the Frequency of Precocious Puberty and Rapidly Progressive Early Puberty Increased in Girls During the COVID-19 Pandemic?
Article in Journal of clinical research in pediatric endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Comparison of central precocious puberty frequency before and during COVID-19: a systematic review and meta-analysis.BMC endocrine disorders · 2024Pooled it
- Central precocious puberty in Türkiye, 2018-2024: national incidence, prevalence, and changes across the COVID-19 period.Frontiers in endocrinology · 2026Article
- Polycystic ovary syndrome and idiopathic central precocious puberty: two sides of the same coin?Endocrine · 2025Review
- Analysis of Risk Factor Changes for Myopia in Korean Adolescents Before and After the COVID-19 Pandemic.Medicina (Kaunas, Lithuania) · 2025Article
- Growing Up in the Pandemic: Examining Associations Between Reproductive Development and Depressive Symptoms in Pre- and Pandemic Girls.Research on child and adolescent psychopathology · 2025Article
- Impact of the COVID-19 pandemic on the incidence of central precocious puberty: A PRISMA-ScR-COMPLIANT scoping review.Archives of endocrinology and metabolism · 2025Article
- Clinical and epidemiological insights into early puberty in Thai girls: a 5-year study.Annals of pediatric endocrinology & metabolism · 2025Article
- Back to normal? A retrospective study on stimulation test and endocrinological diagnosis before, during and after COVID-19 pandemics.Frontiers in endocrinology · 2025Article
- Development and comparison of multivariate diagnostic models for rapidly progressive central precocious puberty in girls: the role of serum osteocalcin.Frontiers in endocrinology · 2025Article
- Precocious puberty, pandemic and beyond.Pituitary · 2024Review
- Article
- Central Precocious Puberty During the COVID-19 Pandemic Period: A Systematic Review of Literature.Cureus · 2024Review
- Pineal cysts may promote pubertal development in girls with central precocious puberty: a single-center study from China.Frontiers in endocrinology · 2024Article
- Effects of Blue Light on Puberty and Ovary in Female RatsJournal of clinical research in pediatric endocrinology · 2023Article
- Endocrinological Involvement in Children and Adolescents Affected by COVID-19: A Narrative Review.Journal of clinical medicine · 2023Review
- Decline in the Age of Menarche in Istanbul Schoolgirls Over the Last 12 YearsJournal of clinical research in pediatric endocrinology · 2023Article
- Pandemic and precocious puberty - a Google trends study.World journal of methodology · 2023Article
- Precocious puberty under stressful conditions: new understanding and insights from the lessons learnt from international adoptions and the COVID-19 pandemic.Frontiers in endocrinology · 2023Review
- Is blue light exposure a cause of precocious puberty in male rats?Frontiers in endocrinology · 2023Article
- COVID-19 pandemic phases and female precocious puberty: The experience of the past 4 years (2019 through 2022) in an Italian tertiary center.Frontiers in endocrinology · 2023Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Early puberty is development of secondary sex characteristics earlier than the expected normal age range. We subjectively observed an increased frequency of early puberty during the Coronavirus disease-2019 (COVID-19) lockdown and aimed to show the clinical, demographic characteristics of the cases and the change in its incidence. Methods: Female patients with central precocious puberty (CPP, n=28) and rapidly progressive early puberty (RPEP, n=61), presenting to our clinic before (January 2019-March 2020) and during the COVID-19 pandemic (April 2020-June 2021) were included. Results: Among 28 CPP cases, six (21%) presented before the pandemic lockdown, whereas 22 (79%) were diagnosed during the COVID-19 pandemic lockdown. While RPEP was seen in 16 (26%) patients before the pandemic, 45 (74%) patients were diagnosed during the lockdown period. Presentation with menarche was seen in 15 RPEP patients; two (13%) were in the prepandemic period and 13 (87%) were in the lockdown period. Chronological age, bone age, bone age to chronological age ratio, height, weight, and body mass index standard deviation scores of patients with RPEP and CPP were similar between the prepandemic and pandemic period. Conclusion: In this cohort, the frequency of CPP and RPP cases were significantly (p<0.001) increased during the COVID-19 pandemic, possibly due to environmental changes.
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