Evidence map›Paper›PMID 35633495›Full record

ArticleVirus genes2022

Isolation and characterization of the novel bacteriophage vB_SmaS_BUCT626 against Stenotrophomonas maltophilia.

Fei Li, Lingxing Li, Yong Zhang, Shiyu Bai, Li Sun, Jingli Guan, Wangmeng Zhang, Xiaogang Cui, Jiao Feng, Yigang Tong

Abstract read
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Article in Virus genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Isolation and characterisation of a novel Stenotrophomonas maltophilia phage vB_SmaS_BCU-1 with evaluation of mammalian cell safety.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  3. Article
  4. Article
  5. Enhanced suppression ofAntimicrobial agents and chemotherapy · 2025
    Article
  6. Enhanced Suppression ofbioRxiv : the preprint server for biology · 2024
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fei Li *College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, 100029, China.
Lingxing Li *Taian City Central Hospital, Taian, 271000, China.
Yong Zhang *Taian City Central Hospital, Taian, 271000, China.
Shiyu BaiTaian City Central Hospital, Taian, 271000, China.
Li SunInstitutes of Biomedical Sciences, Shanxi University, Taiyuan, 030006, China.
Jingli GuanTaian City Central Hospital, Taian, 271000, China.
Wangmeng ZhangTaian City Central Hospital, Taian, 271000, China. zhangwangmeng009@126.com.
Xiaogang CuiInstitutes of Biomedical Sciences, Shanxi University, Taiyuan, 030006, China. helloxiaogangcui@sxu.edu.cn.
Jiao FengInstitutes of Biomedical Sciences, Shanxi University, Taiyuan, 030006, China. fengjiao-1219@163.com.
Yigang TongCollege of Life Science and Technology, Beijing University of Chemical Technology, Beijing, 100029, China. tong.yigang@gmail.com.

Funding

National Key Research and Development Program of China 2018YFA0903000National Natural Science Foundation of China 82002207Natural Science Foundation of Shanxi Province 201901D211136Shanxi Province Science Foundation for Youths 201801D221285Technology Research and Development Program of Taian 2018NS0140
6 · The paper itself

Abstract

Stenotrophomonas maltophilia has been recognized as an emerging global opportunistic pathogen, and it is intrinsically resistant to most antibiotics, which makes the limited choice for treating S. maltophilia infections. Bacteriophage with the proper characterization is considered as a promising alternative treatment option to control S. maltophilia infections. In this study, we isolated a novel Siphoviridae bacteriophage vB_SmaS_BUCT626 with lytic activity against S. maltophilia. Phage vB_SmaS_BUCT626 can lysis 10 of 20 S. maltophilia and was relatively stable at a wide range of temperatures (4-70 °C) and pH values (3.0-13.0) and exhibited good tolerance to chloroform. The genome of phage vB_SmaS_BUCT626 was a 61,662-bp linear double-stranded DNA molecule with a GC content of 56.2%, and contained 100 open-reading frames. It carried no antibiotic resistance, toxin, virulence-related genes, or lysogen-formation gene clusters. Together, these characteristics make phage vB_SmaS_BUCT626, a viable candidate as a biocontrol agent against S. maltophilia infection.

Indexed as

BacteriophagesSiphoviridaeStenotrophomonas maltophiliaChloroformGenome, ViralChloroformBacteriophageGenome sequencingSequence analysisStenotrophomonas maltophilia

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.