Evidence map›Paper›PMID 35633415›Full record

ArticlePlant foods for human nutrition (Dordrecht, Netherlands)2022

The Immunomodulating Effect of Phlorotannins from a Brown Alga, Eisenia nipponica, on Mice Stimulated with Ovalbumin through T Cell Regulation.

Yoshimasa Sugiura, Yuta Matsuura, Hirotaka Katsuzaki, Makoto Kakinuma, Hideomi Amano, Masakatsu Usui, Ryusuke Tanaka, Teruo Matsushita, Masaaki Miyata

Abstract read
PubMed Publisher
In one paragraph

Article in Plant foods for human nutrition (Dordrecht, Netherlands), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yoshimasa SugiuraDepartment of Food Science and Technology, National Research and Development Agency, Japan Fisheries Research and Education Agency, National Fisheries University, Shimonoseki, Yamaguchi, Japan. ysugiura@fish-u.ac.jp.ORCID http://orcid.org/0000-0001-6525-3066
Yuta MatsuuraResearch Center for Fish Diseases, National Research Institute of Aquaculture, Minami-ise, Mie, Japan.
Hirotaka KatsuzakiGraduate School of Bioresources, Mie University, Tsu, Mie, Japan.
Makoto KakinumaGraduate School of Bioresources, Mie University, Tsu, Mie, Japan.
Hideomi AmanoGraduate School of Bioresources, Mie University, Tsu, Mie, Japan.
Masakatsu UsuiDepartment of Food Science and Technology, National Research and Development Agency, Japan Fisheries Research and Education Agency, National Fisheries University, Shimonoseki, Yamaguchi, Japan.
Ryusuke TanakaDepartment of Food Science and Technology, National Research and Development Agency, Japan Fisheries Research and Education Agency, National Fisheries University, Shimonoseki, Yamaguchi, Japan.
Teruo MatsushitaDepartment of Food Science and Technology, National Research and Development Agency, Japan Fisheries Research and Education Agency, National Fisheries University, Shimonoseki, Yamaguchi, Japan.
Masaaki MiyataDepartment of Food Science and Technology, National Research and Development Agency, Japan Fisheries Research and Education Agency, National Fisheries University, Shimonoseki, Yamaguchi, Japan.
National Fisheries University · JPMie University · JPJapan Fisheries Research and Education Agency · JP

Funding

Japan Society for the Promotion of Science 17K07951Japan Society for the Promotion of Science 23880036Japan Society for the Promotion of Science 25850099
6 · The paper itself

Abstract

The immunomodulating effect of phlorotannin was investigated in mice stimulated by ovalbumin. When analyzing the main components of phlorotannin concentrate (PTC) from Eisenia nipponica, seven phlorotannins [eckol, 6,6'-bieckol, 6,8'-bieckol, 8,8'-bieckol, dieckol, phlorofucofuroeckol (PFF)-A, and PFF-B] were detected. These phlorotannins accounted for approximately 80% of PTC. Oral administration of PTC to mice daily for 21 days reduced serum immunoglobulin E (IgE) and total IgG

Indexed as

PhaeophyceaeT-LymphocytesAnimalsCytokinesMiceOvalbuminRNA, MessengerCytokinesOvalbuminRNA, MessengerAntiallergyBrown algaeImmunomodulationPhlorotannins

Identifiers

PMID35633415
OpenAlexW4281705026

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.