ArticleEuropean archives of psychiatry and clinical neuroscience2023
Association between chemosensory impairment with neuropsychiatric morbidity in post-acute COVID-19 syndrome: results from a multidisciplinary cohort study.
Article in European archives of psychiatry and clinical neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Long-term neurological and cognitive impact of COVID-19: a systematic review and meta-analysis in over 4 million patients.BMC neurology · 2025Pooled it
- [Cognition and Long COVID: A PRISMA Systematic Review of Longitudinal Studies].Revista de neurologia · 2025Pooled it
- Neurological and neuropsychiatric manifestations of post-COVID-19 condition in South America: a systematic review of the literature.Arquivos de neuro-psiquiatria · 2024Pooled it
- The assessment of qualitative olfactory dysfunction in COVID-19 patients: a systematic review of tools and their content validity.Frontiers in psychology · 2023Pooled it
- Longitudinal evaluation of neurocognitive outcomes in a cohort with persistent post-COVID olfactory dysfunction.Scientific reports · 2026Article
- Persistent olfactory dysfunction as an indicator of cognitive impairment in long COVID-19 syndrome: implications for monitoring and rehabilitation.European archives of psychiatry and clinical neuroscience · 2026Article
- Review
- Persistent Post-COVID-19 Olfactory Dysfunction and Its Association with Autonomic Nervous System Function: A Case-Control Study.Diseases (Basel, Switzerland) · 2024Article
- Factors associated with older adults' cognitive decline 6 months after gamma-variant SARS-CoV-2 infection.Frontiers in neurology · 2024Article
- Data-driven, cross-disciplinary collaboration: lessons learned at the largest academic health center in Latin America during the COVID-19 pandemic.Frontiers in public health · 2024Article
- Post-COVID-19 condition: systemic inflammation and low functional exercise capacity.Frontiers in nutrition · 2024Article
- Long COVID: neurological manifestations - an updated narrative review.Dementia & neuropsychologia · 2024Review
- Neurological Consequences, Mental Health, Physical Care, and Appropriate Nutrition in Long-COVID-19.Cellular and molecular neurobiology · 2023Review
- Insight into the long-term psychological impacts of the COVID-19 pandemic.European archives of psychiatry and clinical neuroscience · 2023Article
- Olfaction and neurocognition after COVID-19: a scoping review.Frontiers in neuroscience · 2023Article
- Association between olfactory dysfunction and mood disturbances with objective and subjective cognitive deficits in long-COVID.Frontiers in psychology · 2023Article
- Cognitive impairment in long-COVID and its association with persistent dysregulation in inflammatory markers.Frontiers in immunology · 2023Article
- Anosmia in COVID-19 could be associated with long-term deficits in the consolidation of procedural and verbal declarative memories.Frontiers in neuroscience · 2022Article
Corrections and comments
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Authors and funding
17 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Preliminary methodologically limited studies suggested that taste and smell known as chemosensory impairments and neuropsychiatric symptoms are associated in post-COVID-19. The objective of this study is to evaluate whether chemosensory dysfunction and neuropsychiatric impairments in a well-characterized post-COVID-19 sample. This is a cohort study assessing adult patients hospitalized due to moderate or severe forms of COVID-19 between March and August 2020. Baseline information includes several clinical and hospitalization data. Further evaluations were made using several different reliable instruments designed to assess taste and smell functions, parosmia, and neuropsychiatric disorders (using standardized psychiatric and cognitive measures). Out of 1800 eligible individuals, 701 volunteers were assessed on this study. After multivariate analysis, patients reporting parosmia had a worse perception of memory performance (p < 0.001). Moderate/severe hypogeusia was significantly associated with a worse performance on the word list memory task (p = 0.012); Concomitant moderate/severe olfactory and gustatory loss during the acute phase of COVID-19 was also significantly associated with episodic memory impairment (p = 0.006). We found a positive association between reported chemosensory (taste and olfaction) abnormalities and cognition dysfunction in post-COVID-19 patients. These findings may help us identify potential mechanisms linking these two neurobiological functions, and also support the speculation on a possible route through which SARS-CoV-2 may reach the central nervous system.
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