Evidence map›Paper›PMID 35633385›Full record

ReviewMikrochimica acta2022

Advanced wearable biosensors for the detection of body fluids and exhaled breath by graphene.

Santoshi U Singh, Subhodeep Chatterjee, Shahbaz Ahmad Lone, Hsin-Hsuan Ho, Kuldeep Kaswan, Kiran Peringeth, Arshad Khan, Yun-Wei Chiang, Sangmin Lee, Zong-Hong Lin

Abstract readReview
In one paragraph

Review in Mikrochimica acta, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Photonic Nanomaterials for Wearable Health Solutions.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Artificial Olfactory Biohybrid System: An Evolving Sense of Smell.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Santoshi U SinghDepartment of Chemistry, National Tsing Hua University, Hsinchu, 30013, Taiwan.
Subhodeep ChatterjeeInstitute of Biomedical Engineering, National Tsing Hua University, Hsinchu, 30013, Taiwan.
Shahbaz Ahmad LoneInstitute of Biomedical Engineering, National Tsing Hua University, Hsinchu, 30013, Taiwan.
Hsin-Hsuan HoInstitute of Biomedical Engineering, National Tsing Hua University, Hsinchu, 30013, Taiwan.
Kuldeep KaswanInstitute of Biomedical Engineering, National Tsing Hua University, Hsinchu, 30013, Taiwan.
Kiran PeringethInstitute of Biomedical Engineering, National Tsing Hua University, Hsinchu, 30013, Taiwan.
Arshad KhanInstitute of Biomedical Engineering, National Tsing Hua University, Hsinchu, 30013, Taiwan.
Yun-Wei ChiangDepartment of Chemistry, National Tsing Hua University, Hsinchu, 30013, Taiwan.
Sangmin LeeSchool of Mechanical Engineering, Chung-Ang University, Seoul, 06974, South Korea. slee98@cau.ac.kr.
Zong-Hong LinInstitute of Biomedical Engineering, National Tsing Hua University, Hsinchu, 30013, Taiwan. linzh@mx.nthu.edu.tw.ORCID http://orcid.org/0000-0002-1793-7858

Funding

Chung-Ang University Chung-Ang University Research Grant in 2021Ministry of Science and Technology, Taiwan 110-2636-E-007-019
6 · The paper itself

Abstract

Given the huge economic burden caused by chronic and acute diseases on human beings, it is an urgent requirement of a cost-effective diagnosis and monitoring process to treat and cure the disease in their preliminary stage to avoid severe complications. Wearable biosensors have been developed by using numerous materials for non-invasive, wireless, and consistent human health monitoring. Graphene, a 2D nanomaterial, has received considerable attention for the development of wearable biosensors due to its outstanding physical, chemical, and structural properties. Moreover, the extremely flexible, foldable, and biocompatible nature of graphene provide a wide scope for developing wearable biosensor devices. Therefore, graphene and its derivatives could be trending materials to fabricate wearable biosensor devices for remote human health management in the near future. Various biofluids and exhaled breath contain many relevant biomarkers which can be exploited by wearable biosensors non-invasively to identify diseases. In this article, we have discussed various methodologies and strategies for synthesizing and pattering graphene. Furthermore, general sensing mechanism of biosensors, and graphene-based biosensing devices for tear, sweat, interstitial fluid (ISF), saliva, and exhaled breath have also been explored and discussed thoroughly. Finally, current challenges and future prospective of graphene-based wearable biosensors have been evaluated with conclusion. Graphene is a promising 2D material for the development of wearable sensors. Various biofluids (sweat, tears, saliva and ISF) and exhaled breath contains many relevant biomarkers which facilitate in identify diseases. Biosensor is made up of biological recognition element such as enzyme, antibody, nucleic acid, hormone, organelle, or complete cell and physical (transducer, amplifier), provide fast response without causing organ harm.

Indexed as

Biosensing TechniquesBody FluidsGraphiteWearable Electronic DevicesBiomarkersHumansBiomarkersGraphiteBiomarkersBody fluidsExhaled breathGrapheneNon-invasive detectionWearable biosensors

Identifiers

PMID35633385
PMCPMC9146825

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.