SynthesisEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2022
Spinal manipulative therapy in older adults with chronic low back pain: an individual participant data meta-analysis.
Synthesis in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 14 citations in OpenAlex.
- Application of variance ratios to assess heterogeneity of spinal manipulative therapy for chronic low back pain: A meta-epidemiological study.PM & R : the journal of injury, function, and rehabilitation · 2026Pooled it
- A systematic review on the associations between low back pain and frailty in community-dwelling older adults.Chiropractic & manual therapies · 2025Pooled it
- Efficacy and safety of musculoskeletal manipulations in elderly population with musculoskeletal disorders: a systematic review.BMJ open · 2025Pooled it
- Efficacy of spinal manipulative therapy in older adults with chronic spinal conditions: an updated systematic review.The Journal of the Canadian Chiropractic Association · 2026Article
- Impact of chiropractic care on opioid use for noncancer spine pain: systematic review and meta-analysis.Pain reports · 2026Review
- From mechanotransduction to manual therapy: advances in piezo/TRP channels and lumbar degeneration.Frontiers in physiology · 2026Review
- Beyond the lungs: patients' experiences of musculoskeletal symptoms and manual therapy in cystic fibrosis care - A qualitative interview study.The Journal of manual & manipulative therapy · 2025Article
- Contextual factors related to aging determine force-based manipulation dosage: a prospective cross-sectional study.Chiropractic & manual therapies · 2025Article
- Kinematic and mechanical assessment of seated lumbar rotation manipulation: force, velocity and orientation in three dimensions.Frontiers in bioengineering and biotechnology · 2025Article
- Article
- The effectiveness of spinal manipulative therapy procedures for spine pain: protocol for a systematic review and network meta-analysis.Chiropractic & manual therapies · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeMany systematic reviews have reported on the effectiveness of spinal manipulative therapy (SMT) for low back pain (LBP) in adults. Much less is known about the older population regarding the effects of SMT.
objectiveTo assess the effects of SMT on pain and function in older adults with chronic LBP in an individual participant data (IPD) meta-analysis.
settingElectronic databases from 2000 until June 2020, and reference lists of eligible trials and related reviews. DESIGN AND SUBJECTS: Randomized controlled trials (RCTs) which examined the effects of SMT in adults with chronic LBP compared to interventions recommended in international LBP guidelines.
methodsAuthors of trials eligible for our IPD meta-analysis were contacted to share data. Two review authors conducted a risk of bias assessment. Primary results were examined in a one-stage mixed model, and a two-stage analysis was conducted in order to confirm findings. MAIN OUTCOMES AND MEASURES: Pain and functional status examined at 4, 13, 26, and 52 weeks.
results10 studies were retrieved, including 786 individuals, of which 261 were between 65 and 91 years of age. There is moderate-quality evidence that SMT results in similar outcomes at 4 weeks (pain: mean difference [MD] - 2.56, 95% confidence interval [CI] - 5.78 to 0.66; functional status: standardized mean difference [SMD] - 0.18, 95% CI - 0.41 to 0.05). Second-stage and sensitivity analysis confirmed these findings.
conclusionSMT provides similar outcomes to recommended interventions for pain and functional status in the older adult with chronic LBP. SMT should be considered a treatment for this patient population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.