Evidence map›Paper›PMID 35633227›Full record

ArticleJournal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine2022

Feasibility of Magnetic Resonance-Guided High-Intensity-Focused Ultrasound (MRgHIFU) Ablation of Stump Neuromas for the Relief of Chronic Postamputation Neuropathic Pain.

Alicia Nachtigal, Ronen Cozakov, Anat Grinfeld, May Haddad, Elon Eisenberg

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Alicia NachtigalDepartment of Radiology, Hillel-Yaffe Medical Center, Hadera, Israel.
Ronen CozakovInstitute of Pain Medicine, Rambam Health Care Campus, Haifa, Israel.
Anat GrinfeldDepartment of Radiology, Rambam Health Care Campus, Haifa, Israel.
May HaddadInstitute of Pain Medicine, Rambam Health Care Campus, Haifa, Israel.
Elon EisenbergRappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel.ORCID https://orcid.org/0000-0003-3748-1349
Rambam Health Care Campus · ILHillel Yaffe Medical Center · ILTechnion – Israel Institute of Technology · IL

Funding

Focused Ultrasound Foundation
6 · The paper itself

Abstract

Up to 70% of limb amputees develop chronic postamputation neuropathic pain (CPANP) which includes phantom pain and residual limb neuropathic pain due to neuroma formation. CPANP often requires invasive procedures aimed at neuroma ablation. Five amputees received 6 noninvasive magnetic resonance-guided high-intensity-focused ultrasound MRgHIFU treatments ExAblate®, Insightec, Tirat-Carmel, Israel). Although ablative temperature (>65°C) at the neuroma was reached in only 1 patient, pain intensity dropped from 5.7 at baseline to 4.3 and back to 5.6 at 3 and 6 month follow-up. Post-treatment bone necrosis was demonstrated in 1 patient. Although no firm conclusion about the effectiveness of MRgHIFU for CPANP could be drawn, further studies are warranted.

Indexed as

High-Intensity Focused Ultrasound AblationNeuralgiaNeuromaAmputation StumpsFeasibility StudiesHumansMagnetic Resonance Spectroscopynerve blockneuropathic painphantom painresidual limb painthermal ablation

Identifiers

PMID35633227
PMCPMC9796504
OpenAlexW4281630059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.