Evidence map›Paper›PMID 35632788›Full record

ArticleViruses2022

SARS-CoV-2 Seroconversion in an Adult Horse with Direct Contact to a COVID-19 Individual.

Nicola Pusterla, Antoine Chaillon, Caroline Ignacio, Davey M Smith, Samantha Barnum, Kaila O Y Lawton, Greg Smith, Bradley Pickering

Open access · goldAbstract readCase Reports
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Improving the ONE HEALTH approach: a lesson from SARS-CoV-2 pandemic.Journal of preventive medicine and hygiene · 2024
    Review
  4. Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Nicola PusterlaDepartment of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA.
Antoine ChaillonDivision of Infectious Diseases and Global Public Health, University of California San Diego, La Jolla, CA 92093, USA.
Caroline IgnacioDivision of Infectious Diseases and Global Public Health, University of California San Diego, La Jolla, CA 92093, USA.
Davey M SmithDivision of Infectious Diseases and Global Public Health, University of California San Diego, La Jolla, CA 92093, USA.
Samantha BarnumDepartment of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA.
Kaila O Y LawtonDepartment of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA.ORCID 0000-0003-2453-0850
Greg SmithNational Center for Foreign Animal Disease, Canadian Food Inspection Agency, Winnipeg, MB R3E 3M4, Canada.
Bradley PickeringNational Center for Foreign Animal Disease, Canadian Food Inspection Agency, Winnipeg, MB R3E 3M4, Canada.
University of California, Davis · USUniversity of California San Diego · USCanadian Food Inspection Agency · CA

Funding

Primary Infection Resource Consortium (PIRC)R24AI106039 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LITTLE, SUSAN JANET · 2013 to 2021
$23.1M
Ethno-epidemiology of HCV, HIV and Overdose associated with Drug Marketsand Drug TourismR01DA049644 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI STRATHDEE, STEFFANIE A. · 2020 to 2024
$8.2M
Integrating HCV services into HIV programs for PWID in IndiaR01AI145555 · NIAID · JOHNS HOPKINS UNIVERSITY · PI MEHTA, SHRUTI H, SOLOMON, SUNIL SUHAS · 2019 to 2024
$6.2M
Brain Myeloid Cells are Sources of HIV-associated Damage and Viral DispersalR01DA055491 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHAILLON, ANTOINE · 2021 to 2025
$3.6M
The HIV-associated Opioid Micro-Environment (HOME) ProjectDP2DA051915 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GIANELLA WEIBEL, SARA · 2020 to 2020
$2.4M
Mentoring Translational Research in HIVK24AI100665 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SMITH, DAVID MITCHELL · 2012 to 2021
$1.5M
NIAID NIH HHS K24 AI100665NIAID NIH HHS R01 AI145555NIAID NIH HHS R24 AI106039NIDA NIH HHS DP2 DA051915NIDA NIH HHS R01 DA049644NIDA NIH HHS R01 DA055491NIH HHS AI306214 and AI100665
6 · The paper itself

Abstract

The authors report on a possible direct exposure to SARS-CoV-2 from a COVID-19-positive individual to an adult horse. The individual, diagnosed with COVID-19 (Delta B.1.617.2), had daily contact to her two horses prior to and during the development of clinical disease. None of the two horses developed abnormal clinical signs or had detectable SARS-CoV-2 in blood, nasal secretion, or feces via RT-qPCR. However, one of the two horses showed close temporal seroconversion to SARS-CoV-2 using a protein-based ELISA and the plaque reduction neutralization test. The results suggest that horses can become silently infected with SARS-CoV-2 following close contact with humans infected with SARS-CoV-2. As a precautionary measure, humans infected with SARS-CoV-2 should avoid close contact with equids and other companion animals during the time of their illness to prevent viral transmission.

Indexed as

COVID-19SARS-CoV-2AnimalsEnzyme-Linked Immunosorbent AssayFemaleHorsesSeroconversionantibodiesCOVID-19horseSARS-CoV-2spillover

Identifiers

PMID35632788
PMCPMC9145940
OpenAlexW4280513654

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.