Evidence map›Paper›PMID 35632780›Full record

ArticleViruses2022

Analysis of Human Papillomavirus (HPV) and Polyomaviruses (HPyVs) in Adenoid Cystic Carcinoma (AdCC) of the Head and Neck Region Reveals Three HPV-Positive Cases with Adenoid Cystic-like Features.

Mark Zupancic, Stefan Holzhauser, Liquin Cheng, Torbjörn Ramqvist, Juan Du, Signe Friesland, Anders Näsman, Tina Dalianis

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mark ZupancicDepartment of Oncology-Pathology, Karolinska Institutet, 17164 Stockholm, Sweden.
Stefan HolzhauserDepartment of Oncology-Pathology, Karolinska Institutet, 17164 Stockholm, Sweden.
Liquin ChengDepartment of Microbiology, Tumour Biology and Cell Biology, Karolinska Institutet, 17177 Stockholm, Sweden.
Torbjörn RamqvistDepartment of Oncology-Pathology, Karolinska Institutet, 17164 Stockholm, Sweden.
Juan DuDepartment of Microbiology, Tumour Biology and Cell Biology, Karolinska Institutet, 17177 Stockholm, Sweden.ORCID 0000-0001-7649-9571
Signe FrieslandDepartment of Oncology-Pathology, Karolinska Institutet, 17164 Stockholm, Sweden.
Anders NäsmanDepartment of Oncology-Pathology, Karolinska Institutet, 17164 Stockholm, Sweden.ORCID 0000-0003-4602-4297
Tina DalianisDepartment of Oncology-Pathology, Karolinska Institutet, 17164 Stockholm, Sweden.
Karolinska Institutet · SEKarolinska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An aetiological role of human papillomavirus (HPV) and/or human polyomaviruses (HPyVs) has been proposed in adenoid cystic carcinoma (AdCC). Moreover, HPV-related multiphenotypic carcinoma (HMSC) was recently introduced as an emerging entity of the sinonasal region. Here, we primarily want to study the role of HPV/HPyV in a large AdCC cohort and, secondly, possibly identify and characterize HMSC. Tumour DNA from 68 patients initially diagnosed with AdCC between 2000 and 2012 was, therefore, tested for 27 HPV types and 10 HPyVs. HPV DNA-positive samples were micromorphologically re-evaluated, further stained for p16

Indexed as

AdenoidsAlphapapillomavirusCarcinoma, Adenoid CysticCarcinoma, Squamous CellPapillomavirus InfectionsParanasal Sinus NeoplasmsPolyomavirusHumansPapillomaviridaeadenoid cystic carcinomabasaloid carcinomahistopathologyHPV-related multiphenotypic sinonasal carcinomahuman papillomavirushuman papillomavirus carcinoma with adenoid cystic-like featureshuman polyomavirusmolecular pathologypathology of tumourssalivary gland malignanciesvirology

Identifiers

PMID35632780
PMCPMC9144058
OpenAlexW4280535088

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.