Evidence map›Paper›PMID 35632742›Full record

ArticleViruses2022

A Novel In Vivo Model of Laryngeal Papillomavirus-Associated Disease Using

Renee E King, Andrea Bilger, Josef Rademacher, Ella T Ward-Shaw, Rong Hu, Paul F Lambert, Susan L Thibeault

Open access · goldAbstract readCase Reports
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. A non-canonical role ofbioRxiv : the preprint server for biology · 2026
    Article
  6. Article
  7. Inhibition of the MRTF-A/SRF signaling axis alleviates vocal fold scarring.Matrix biology : journal of the International Society for Matrix Biology · 2025
    Article
  8. Article
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  12. Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Renee E KingMcArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin-Madison, Madison, WI 53705, USA.ORCID 0000-0002-6540-3834
Andrea BilgerMcArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin-Madison, Madison, WI 53705, USA.ORCID 0000-0002-4838-4731
Josef RademacherDepartment of Surgery, University of Wisconsin-Madison, Madison, WI 53705, USA.
Ella T Ward-ShawMcArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin-Madison, Madison, WI 53705, USA.
Rong HuDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI 53705, USA.
Paul F LambertMcArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin-Madison, Madison, WI 53705, USA.ORCID 0000-0001-7983-2755
Susan L ThibeaultDepartment of Surgery, University of Wisconsin-Madison, Madison, WI 53705, USA.ORCID 0000-0002-9046-4356
University of Wisconsin–Madison · US

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Justine Yang Bruce · 1985 to 2026
$142.6M
Visualizing EBV and HCMV DNA Dynamics During InfectionP01CA022443 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Paul F. Lambert · 1985 to 2026
$53.1M
Engineering the Vocal Fold MucosaR01DC004336 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI Susan Lynn Thibeault · 2000 to 2026
$14.6M
Project 3: Modulation of the head and neck tumor immune microenvironment by targeting the TAM family of receptorsP50CA278595 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI David J Beebe · 2022 to 2026
$12.5M
Project 4: Role of Receptor Tyrosine Kinase AXL in HNSCC Therapy ResistanceP50DE026787 · NIDCR · UNIVERSITY OF WISCONSIN-MADISON · PI HARARI, PAUL M · 2016 to 2020
$10.8M
Defining Drivers of HPV-associated CarcinogenesisR35CA210807 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Paul F. Lambert · 2017 to 2026
$9.2M
UW Surgical Oncology Research Training Program (UW-SORT)T32CA090217 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Muhammed Murtaza, Heather B Neuman · 2001 to 2026
$8.3M
University of Wisconsin Voice Research Training Program (T32)T32DC009401 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI Susan Lynn Thibeault · 2009 to 2026
$6.3M
Vocal fold epithelial barrier and proliferation in laryngeal papillomatosisF31DC018184 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI KING, RENEE · 2019 to 2021
$73k
NCI NIH HHS P01 CA022443NCI NIH HHS P30 CA014520NCI NIH HHS P50 CA278595NCI NIH HHS R35 CA210807NCI NIH HHS T32 CA090217NIDCD NIH HHS F31 DC018184NIDCD NIH HHS R01 DC004336NIDCD NIH HHS T32 DC009401NIDCR NIH HHS P50 DE026787NIH HHS F31 DC018184NIH HHS P01 CA022443NIH HHS P30 CA014520NIH HHS P50 DE026787NIH HHS R01 DC004336NIH HHS R35 CA210807NIH HHS T32 CA090217NIH HHS T32 DC009401
6 · The paper itself

Abstract

Recurrent respiratory papillomatosis (RRP), caused by laryngeal infection with low-risk human papillomaviruses, has devastating effects on vocal communication and quality of life. Factors in RRP onset, other than viral presence in the airway, are poorly understood. RRP research has been stalled by limited preclinical models. The only known papillomavirus able to infect laboratory mice,

Indexed as

Laryngeal DiseasesLarynxViruses, UnclassifiedAnimalsMiceMice, NudeMice, SCIDPapillomaviridaePapillomavirus InfectionsQuality of LifeRespiratory Tract InfectionslaryngoscopylarynxMmuPV1mousepapillomavirusrecurrent respiratory papillomatosisRRPvocal folds

Identifiers

PMID35632742
PMCPMC9147793
OpenAlexW4229373629

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.