Evidence map›Paper›PMID 35632613›Full record

Observational studyViruses2022

Surveillance of Viral Encephalitis in the Context of COVID-19: A One-Year Observational Study among Hospitalized Patients in Dakar, Senegal.

Jamil Kahwagi, Al Ousseynou Seye, Ahmadou Bamba Mbodji, Rokhaya Diagne, El Hadji Mbengue, Maouly Fall, Soa Fy Andriamandimby, Ava Easton, Martin Faye, Gamou Fall and 15 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Systematic review with meta-analysis of active herpesvirus infections in patients with COVID-19: Old players on the new field.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2023
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Global Landscape of Encephalitis: Key Priorities to Reduce Future Disease Burden.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 4 institutions in 3 countries.

Jamil KahwagiClinique de Neurosciences Ibrahima Pierre Ndiaye, Centre Hospitalier National Universitaire de Fann, Dakar 10700, Senegal.
Al Ousseynou SeyeVirology Department, Institut Pasteur de Dakar, 36, Avenue Pasteur, BP 220, Dakar 12900, Senegal.
Ahmadou Bamba MbodjiClinique de Neurosciences Ibrahima Pierre Ndiaye, Centre Hospitalier National Universitaire de Fann, Dakar 10700, Senegal.
Rokhaya DiagneClinique de Neurosciences Ibrahima Pierre Ndiaye, Centre Hospitalier National Universitaire de Fann, Dakar 10700, Senegal.
El Hadji MbengueClinique de Neurosciences Ibrahima Pierre Ndiaye, Centre Hospitalier National Universitaire de Fann, Dakar 10700, Senegal.
Maouly FallCentre Hospitalier National de Pikine, Pikine 16000, Senegal.
Soa Fy AndriamandimbyInstitut Pasteur de Madagascar, Antananarivo 101, Madagascar.
Ava EastonEncephalitis Society, North Yorkshire YO17 7DT, UK.
Martin FayeVirology Department, Institut Pasteur de Dakar, 36, Avenue Pasteur, BP 220, Dakar 12900, Senegal.ORCID 0000-0003-3207-6344
Gamou FallVirology Department, Institut Pasteur de Dakar, 36, Avenue Pasteur, BP 220, Dakar 12900, Senegal.ORCID 0000-0001-5035-1325
Ndongo DiaVirology Department, Institut Pasteur de Dakar, 36, Avenue Pasteur, BP 220, Dakar 12900, Senegal.
Babacar NdiayeVirology Department, Institut Pasteur de Dakar, 36, Avenue Pasteur, BP 220, Dakar 12900, Senegal.
Momo Banda NdiayeClinique de Neurosciences Ibrahima Pierre Ndiaye, Centre Hospitalier National Universitaire de Fann, Dakar 10700, Senegal.
Alle GueyeClinique de Neurosciences Ibrahima Pierre Ndiaye, Centre Hospitalier National Universitaire de Fann, Dakar 10700, Senegal.
Serigne Saliou MbackeClinique de Neurosciences Ibrahima Pierre Ndiaye, Centre Hospitalier National Universitaire de Fann, Dakar 10700, Senegal.
Fatou KaneClinique de Neurosciences Ibrahima Pierre Ndiaye, Centre Hospitalier National Universitaire de Fann, Dakar 10700, Senegal.
Mohamed Inejih El GhouriechyClinique de Neurosciences Ibrahima Pierre Ndiaye, Centre Hospitalier National Universitaire de Fann, Dakar 10700, Senegal.
Ensene Investigators
Lala Bouna SeckClinique de Neurosciences Ibrahima Pierre Ndiaye, Centre Hospitalier National Universitaire de Fann, Dakar 10700, Senegal.
Ndiaga Matar GayeClinique de Neurosciences Ibrahima Pierre Ndiaye, Centre Hospitalier National Universitaire de Fann, Dakar 10700, Senegal.
Amadou Alpha SallVirology Department, Institut Pasteur de Dakar, 36, Avenue Pasteur, BP 220, Dakar 12900, Senegal.
Moustapha NdiayeVirology Department, Institut Pasteur de Dakar, 36, Avenue Pasteur, BP 220, Dakar 12900, Senegal.
Ousmane FayeVirology Department, Institut Pasteur de Dakar, 36, Avenue Pasteur, BP 220, Dakar 12900, Senegal.
Amadou Gallo DiopClinique de Neurosciences Ibrahima Pierre Ndiaye, Centre Hospitalier National Universitaire de Fann, Dakar 10700, Senegal.
Jean-Michel HeraudVirology Department, Institut Pasteur de Dakar, 36, Avenue Pasteur, BP 220, Dakar 12900, Senegal.ORCID 0000-0003-1107-0859
Institut Pasteur de Dakar · SNCentre Hospitalier National Universitaire de Fann · SNInstitut Pasteur de Madagascar · MGUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The burden of encephalitis and its associated viral etiology is poorly described in Africa. Moreover, neurological manifestations of COVID-19 are increasingly reported in many countries, but less so in Africa. Our prospective study aimed to characterize the main viral etiologies of patients hospitalized for encephalitis in two hospitals in Dakar. From January to December 2021, all adult patients that met the inclusion criteria for clinical infectious encephalitis were enrolled. Cerebrospinal fluids, blood, and nasopharyngeal swabs were taken and tested for 27 viruses. During the study period, 122 patients were enrolled. Viral etiology was confirmed or probable in 27 patients (22.1%), with SARS-CoV-2 (n = 8), HSV-1 (n = 7), HHV-7 (n = 5), and EBV (n = 4) being the most detected viruses. Age groups 40-49 was more likely to be positive for at least one virus with an odds ratio of 7.7. The mortality was high among infected patients, with 11 (41%) deaths notified during hospitalization. Interestingly, SARS-CoV-2 was the most prevalent virus in hospitalized patients presenting with encephalitis. Our results reveal the crucial need to establish a country-wide surveillance of encephalitis in Senegal to estimate the burden of this disease in our population and implement strategies to improve care and reduce mortality.

Indexed as

COVID-19EncephalitisEncephalitis, ViralVirusesAdultHumansProspective StudiesSARS-CoV-2SenegalAfricaencephalitisherpetic virusesSARS-CoV-2Senegalvirus

Identifiers

PMID35632613
PMCPMC9145710
OpenAlexW4224319351

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.