Evidence map›Paper›PMID 35632499›Full record

ArticleVaccines2022

Increased Receptor Affinity and Reduced Recognition by Specific Antibodies Contribute to Immune Escape of SARS-CoV-2 Variant Omicron.

Anne-Cathrine S Vogt, Gilles Augusto, Byron Martina, Xinyue Chang, Gheyath Nasrallah, Daniel E Speiser, Monique Vogel, Martin F Bachmann, Mona O Mohsen

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 4 countries.

Anne-Cathrine S VogtDepartment of BioMedical Research, University of Bern, 3010 Bern, Switzerland.
Gilles AugustoDepartment of BioMedical Research, University of Bern, 3010 Bern, Switzerland.
Byron MartinaDepartment of Viroscience, Erasmus Medical Center, 3015 Rotterdam, The Netherlands.
Xinyue ChangDepartment of BioMedical Research, University of Bern, 3010 Bern, Switzerland.
Gheyath NasrallahBiomedical Research Complex, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0001-9252-1038
Daniel E SpeiserDepartment of BioMedical Research, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0003-2031-3250
Monique VogelDepartment of BioMedical Research, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0002-5219-4033
Martin F BachmannDepartment of BioMedical Research, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0003-4370-2099
Mona O MohsenDepartment of BioMedical Research, University of Bern, 3010 Bern, Switzerland.
University of Bern · CHArtemis One Health Research Foundation · NLQatar University · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this report, we mechanistically reveal how the Variant of Concern (VOC) SARS-CoV-2 Omicron (B.1.1.529) escapes neutralizing antibody responses, by physio-chemical characterization of this variant in comparison to the wild-type Wuhan and the Delta variant (B.1.617.2). Convalescent sera, as well as sera obtained from participants who received two or three doses of mRNA vaccines (Moderna-mRNA-1273

Indexed as

antibodyDeltaOmicronSARS-CoV-2

Identifiers

PMID35632499
PMCPMC9147318
OpenAlexW4280587804

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.