Evidence map›Paper›PMID 35632487›Full record

ArticleVaccines2022

Immunity after HPV Vaccination in Patients after Sexual Initiation.

Dominik Pruski, Małgorzata Łagiedo-Żelazowska, Sonja Millert-Kalińska, Jan Sikora, Robert Jach, Marcin Przybylski

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Dominik PruskiDepartment of Obstetrics and Gynecology, District Public Hospital in Poznan, 60-479 Poznań, Poland.ORCID 0000-0001-5821-5731
Małgorzata Łagiedo-ŻelazowskaDepartment of Immunology, Chair of Pathomorphology and Clinical Immunology, Poznan University of Medical Sciences, 60-806 Poznań, Poland.ORCID 0000-0003-1081-7199
Sonja Millert-KalińskaDepartment of Obstetrics and Gynecology, District Public Hospital in Poznan, 60-479 Poznań, Poland.ORCID 0000-0002-8291-3879
Jan SikoraDepartment of Immunology, Chair of Pathomorphology and Clinical Immunology, Poznan University of Medical Sciences, 60-806 Poznań, Poland.
Robert JachDepartment of Gynecological Endocrinology, Jagiellonian University Medical College, 31-008 Cracow, Poland.
Marcin PrzybylskiDepartment of Obstetrics and Gynecology, District Public Hospital in Poznan, 60-479 Poznań, Poland.
Poznan University of Medical Sciences · PLJagiellonian University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccinations against human papillomavirus (HPV) are included in the primary prevention of precancerous intraepithelial lesions and HPV-related cancers. Despite the undeniable effectiveness of vaccination in the juvenile population, there is still little research on the effect in patients after sexual initiation. Our study aims to assess anti-HPV (L1 HPV) antibodies in healthy patients and diagnosed cervical pathology after 9-valent vaccination. We provide a prospective, ongoing 12-month, non-randomised pilot study in which 89 subjects were enrolled. We used an enzyme-linked immunosorbent assay to determine IgG class antibodies to HPV. We noted significantly higher levels of antibodies in vaccinated individuals than in the unvaccinated control group. The above work shows that vaccination against HPV might be beneficial in patients after sexual initiation as well as in those already diagnosed with HPV or SIL infection.

Indexed as

9-valent vaccinationHPV serum antibodiesL1 HPVsquamous intraepithelial neoplasia

Identifiers

PMID35632487
PMCPMC9144159
OpenAlexW4229378120

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.