Evidence map›Paper›PMID 35632392›Full record

ArticleVaccines2022

Clinical and Laboratory Features in the Israeli Population with COVID-19 Infection after Pfizer-BioNTech mRNA Booster Vaccination.

Ariel Israel, Eugene Merzon, Yotam Shenhar, Ilan Green, Avivit Golan-Cohen, Alejandro A Schäffer, Eytan Ruppin, Shlomo Vinker, Eli Magen

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Ariel IsraelLeumit Research Institute & Department of Family Medicine, Leumit Health Services, Tel Aviv-Yafo 6473817, Israel.
Eugene MerzonLeumit Research Institute & Department of Family Medicine, Leumit Health Services, Tel Aviv-Yafo 6473817, Israel.
Yotam ShenharLeumit Research Institute & Department of Family Medicine, Leumit Health Services, Tel Aviv-Yafo 6473817, Israel.
Ilan GreenLeumit Research Institute & Department of Family Medicine, Leumit Health Services, Tel Aviv-Yafo 6473817, Israel.
Avivit Golan-CohenLeumit Research Institute & Department of Family Medicine, Leumit Health Services, Tel Aviv-Yafo 6473817, Israel.ORCID 0000-0003-2406-6402
Alejandro A SchäfferCancer Data Science Laboratory, National Cancer Institute, Bethesda, MD 20814, USA.ORCID 0000-0002-2147-8033
Eytan RuppinDepartment of Family Medicine, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv-Yafo 6997801, Israel.
Shlomo VinkerLeumit Research Institute & Department of Family Medicine, Leumit Health Services, Tel Aviv-Yafo 6473817, Israel.
Eli MagenLeumit Research Institute & Department of Family Medicine, Leumit Health Services, Tel Aviv-Yafo 6473817, Israel.ORCID 0000-0002-7713-423X
Tel Aviv University · ILClalit Health Services · ILAriel University · ILBen-Gurion University of the Negev · ILNational Cancer Institute · US

Funding

Discovering Affective Drug Combinations for Treating Covid-19ZIABC012000 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI RUPPIN, EYTAN · 2020 to 2022
$2.3M
6 · The paper itself

Abstract

Background: Immune protection following either vaccination or infection with SARS-CoV-2 decreases over time. Objective: We aim to describe clinical and sociodemographic characteristics associated with COVID-19 infection at least 14 days after booster vaccination in the Israeli population. Methods: We conducted a population-based study among adult members of Leumit Health Services (LHS) in Israel. Nasopharyngeal swabs were examined for SARS-CoV-2 by real-time RT-PCR. The hematological and biochemical parameters in the peripheral blood before booster vaccination were evaluated. Results: Between 1 February 2021 and 30 November 2021, 136,683 individuals in LHS were vaccinated with a booster (third dose) of the BNT162b2 vaccine. Of these, 1171 (0.9%) were diagnosed with COVID-19 by testing positive for SARS-CoV-2 RT-PCR at least >14 days after the booster vaccination. The COVID-19-positive group was characterized by higher rates of chronic kidney disease than the matched COVID-19-negative group (43 (3.7%) vs. 3646 (2.7%); p = 0.039). Anemia, lower peripheral blood lymphocytes, monocytes, basophils, C3 Complement, cholesterol, and prothrombin time were also associated with COVID-19 after booster vaccination. Conclusion: People with chronic kidney disease and anemia should be included in possible future annual SARS-CoV-2 vaccination recommendations.

Indexed as

BNT162b2convalescentsinfectionmRNASARS-CoV-2vaccine

Identifiers

PMID35632392
PMCPMC9145987
OpenAlexW4224278626

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.