Evidence map›Paper›PMID 35632090›Full record

ArticleSensors (Basel, Switzerland)2022

4-Dimethylaminoantipyrine as a Broad Electrochemical Indicator for Immunosensors Platform.

Francielli C C Melo, Renata P Alves, Anderson L Valle, Fabiana de A A Santos, Ana Carolina S Dias, Isabela M B Goulart, Eduardo G A Oliveira, Guedmiller S Oliveira, Luciano P Rodrigues, Luiz R Goulart

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Francielli C C MeloLaboratory of Nanobiotechnology, Institute of Biotechnology, Federal University of Uberlândia, Avenida Amazonas s/n Bl. 2E, sl. 248, Uberlândia 38402-022, Minas Gerais, Brazil.ORCID 0000-0002-3995-8852
Renata P AlvesBiological Science, Universidade Federal do Triângulo Mineiro, Avenida Antônio Baiano, 150, Cidade Nova, Iturama 38280-000, Minas Gerais, Brazil.ORCID 0000-0003-2411-614X
Anderson L ValleLaboratory of Nanobiotechnology, Institute of Biotechnology, Federal University of Uberlândia, Avenida Amazonas s/n Bl. 2E, sl. 248, Uberlândia 38402-022, Minas Gerais, Brazil.
Fabiana de A A SantosLaboratory of Nanobiotechnology, Institute of Biotechnology, Federal University of Uberlândia, Avenida Amazonas s/n Bl. 2E, sl. 248, Uberlândia 38402-022, Minas Gerais, Brazil.ORCID 0000-0002-5049-4075
Ana Carolina S DiasLaboratory of Nanobiotechnology, Institute of Biotechnology, Federal University of Uberlândia, Avenida Amazonas s/n Bl. 2E, sl. 248, Uberlândia 38402-022, Minas Gerais, Brazil.
Isabela M B GoulartNational Reference Center for Sanitary Dermatology and Leprosy, Clinics Hospital, School of Medicine, Federal University of Uberlândia, R. Capricórnio, 94-Jardim Brasília, Uberlândia 38401-404, Minas Gerais, Brazil.ORCID 0000-0003-2319-3223
Eduardo G A OliveiraInstitute of Chemistry, Federal University of Uberlândia, Avenida João Naves de Ávila, 2121, Bloco 5T, sala 204, Uberlândia 38400-902, Minas Gerais, Brazil.ORCID 0000-0002-7075-8189
Guedmiller S OliveiraInstitute of Chemistry, Federal University of Uberlândia, Avenida João Naves de Ávila, 2121, Bloco 5T, sala 204, Uberlândia 38400-902, Minas Gerais, Brazil.ORCID 0000-0001-7441-4263
Luciano P RodriguesInstitute of Engineering Science and Technology, Federal University of the Jequitinhonha and Mucuri Valleys, Av. Um, n. 4.050-Cidade Universitária, Janaúba 39447-790, Minas Gerais, Brazil.ORCID 0000-0002-9488-5000
Luiz R GoulartLaboratory of Nanobiotechnology, Institute of Biotechnology, Federal University of Uberlândia, Avenida Amazonas s/n Bl. 2E, sl. 248, Uberlândia 38402-022, Minas Gerais, Brazil.ORCID 0000-0002-1803-4861
Universidade Federal de Uberlândia · BRUniversidade Federal dos Vales do Jequitinhonha e Mucuri · BRUniversidade Federal do Triângulo Mineiro · BR

Funding

Fundação de Amparo à Pesquisa do Estado de Minas Gerais CBB-APQ-03613-17National Council for Scientific and Technological Development 465669/2014-0
6 · The paper itself

Abstract

Here, we describe 4-dimethylaminoantipyrine (4-DMAA)-mediated interfacing as a broad biochemical indicator to stabilize and promote the higher response of electrodes for immunological detection. We hypothesized that the improved biological interactions of 4-DMAA with electrodes and biological samples may be due to the interaction properties of the benzene and pyrazole chemical groups with graphite and proteins, respectively. In order to demonstrate that 4-DMAA could be used as a general indicator in electrochemical immunoassays, we used peptides as probes for the diagnosis of four neglected tropical infectious diseases

Indexed as

Biosensing TechniquesGraphiteAminopyrineElectrodesHumansImmunoassayAminopyrineGraphite4-dimethylaminoantipyrinediagnosiselectrochemical indicatorelectrolyteimmunosensorpeptide probe

Identifiers

PMID35632090
PMCPMC9146155
OpenAlexW4280606495

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.