Evidence map›Paper›PMID 35632018›Full record

ArticleSensors (Basel, Switzerland)2022

Design and Characterization of an RF Applicator for In Vitro Tests of Electromagnetic Hyperthermia.

Riccardo Ferrero, Ioannis Androulakis, Luca Martino, Robin Nadar, Gerard C van Rhoon, Alessandra Manzin

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Computational Design of a Thermal Applicator for Brain Hyperthermia Controlled by Capacitor Positioning in Loop Coils.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Riccardo FerreroIstituto Nazionale di Ricerca Metrologica (INRIM), 10135 Torino, Italy.ORCID 0000-0001-9243-2975
Ioannis AndroulakisDepartment of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0003-4816-7048
Luca MartinoIstituto Nazionale di Ricerca Metrologica (INRIM), 10135 Torino, Italy.
Robin NadarDepartment of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center, 3015 GD Rotterdam, The Netherlands.
Gerard C van RhoonDepartment of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0002-7365-5783
Alessandra ManzinIstituto Nazionale di Ricerca Metrologica (INRIM), 10135 Torino, Italy.ORCID 0000-0002-4078-2321
Erasmus MC Cancer Institute · NLIstituto Nazionale di Ricerca Metrologica · IT

Funding

European Metrology Programme for Innovation and Research 18HLT06 RaCHy
6 · The paper itself

Abstract

The evaluation of the biological effects of therapeutic hyperthermia in oncology and the precise quantification of thermal dose, when heating is coupled with radiotherapy or chemotherapy, are active fields of research. The reliable measurement of hyperthermia effects on cells and tissues requires a strong control of the delivered power and of the induced temperature rise. To this aim, we have developed a radiofrequency (RF) electromagnetic applicator operating at 434 MHz, specifically engineered for in vitro tests on 3D cell cultures. The applicator has been designed with the aid of an extensive modelling analysis, which combines electromagnetic and thermal simulations. The heating performance of the built prototype has been validated by means of temperature measurements carried out on tissue-mimicking phantoms and aimed at monitoring both spatial and temporal temperature variations. The experimental results demonstrate the capability of the RF applicator to produce a well-focused heating, with the possibility of modulating the duration of the heating transient and controlling the temperature rise in a specific target region, by simply tuning the effectively supplied power.

Indexed as

Hyperthermia, InducedRadio WavesIn Vitro TechniquesPhantoms, ImagingTemperaturecoaxial cableelectromagnetic hyperthermiaelectromagnetic modellingphantomsRF applicatorTEM modetemperature measurementsthermal modellingthermal therapies

Identifiers

PMID35632018
PMCPMC9148047
OpenAlexW4280601848

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.